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Browsing by Author "Wade, Michael S"

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A novel angiotensin I-converting enzyme mutation (S333W) impairs N-domain enzymatic cleavage of the anti-fibrotic peptide, AcSDKP

Author: Danilov, Sergei M ; Wade, Michael S ; Schwager, Sylva L ; Douglas, Ross G ; Nesterovitch, Andrew B ; Popova, Isolda A ; Hogarth, Kyle D ; Bhardwaj, Nakul ; Schwartz, David E ; Sturrock, Edward D ; Garcia, Joe G N Date: 2014 BACKGROUND: Angiotensin I-converting enzyme (ACE) has two functional N- and C-domain active centers that display differences in the metabolism of biologically-active peptides including the hemoregulatory tetrapeptide, Ac-SDKP, hydrolysed ... Read more c b

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