Browsing by Author "Van Zyl-Smit, Richard N"

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Feasibility and diagnostic utility of antigen-specific interferon-gamma responses for rapid immunodiagnosis of tuberculosis using induced sputum

Author: Cashmore, Tamaryn J ; Peter, Jonathan G ; Van Zyl-Smit, Richard N ; Semple, Patricia L ; Maredza, Alice ; Meldau, Richard ; Zumla, Alimuddin ; Nurse, Barbara ; Dheda, Keertan Date: 2010 BACKGROUND: The diagnosis of smear-negative or sputum-scarce tuberculosis (TB) is problematic as culture takes several weeks and representative biological samples are difficult to obtain. RD-1 antigen-specific interferon-γ release assays ... Read more c b
Within-subject variability of interferon-g assay results for tuberculosis and boosting effect of tuberculin skin testing: a systematic review

Author: Van Zyl-Smit, Richard N ; Zwerling, Alice ; Dheda, Keertan ; Pai, Madhukar Date: 2009 BACKGROUND: Variability in interferon-gamma release assays (IGRAs) results for tuberculosis has implications for interpretation of results close to the cut-point, and for defining thresholds for test conversion and reversion. However, little ... Read more c b

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