Browsing by Author "Steele, Chad"

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The beta-glucan receptor dectin-1 recognizes specific morphologies of Aspergillus fumigatus

Author: Steele, Chad ; Rapaka, Rekha R ; Metz, Allison ; Pop, Shannon M ; Williams, David L ; Gordon, Siamon ; Kolls, Jay K ; Brown, Gordon D Date: 2005 Alveolar macrophages represent a first-line innate host defense mechanism for clearing inhaled Aspergillus fumigatus from the lungs, yet contradictory data exist as to which alveolar macrophage recognition receptor is critical for innate ... Read more c b
Characterisation of innate fungal recognition in the lung

Author: Faro-Trindade, Inês ; Willment, Janet A ; Kerrigan, Ann M ; Redelinghuys, Pierre ; Hadebe, Sabelo ; Reid, Delyth M ; Srinivasan, Naren ; Wainwright, Helen ; Lang, Dirk M ; Steele, Chad Date: 2012 The innate recognition of fungi by leukocytes is mediated by pattern recognition receptors (PRR), such as Dectin-1, and is thought to occur at the cell surface triggering intracellular signalling cascades which lead to the induction of ... Read more c b

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