Browsing by Author "Simonsson, USH"

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Optimization of 1st-line antituberculosis dosing regimens using a population pharmacokinetic approach: food effects, drug combinations and pharmacological effects

Author: Zvada, Simbarashe Peter Date: 2014 The aim of this thesis was to evaluate optimal doses of 1st-line antituberculosis dosing regimens using a population pharmacokinetic approach, quantify food effects, drug combinations and pharmacological effects. The population pharmacokinetics ... Read more
Population pharmacokinetics of lopinavir and ritonavir in combination with rifampicin-based antitubercular treatment in HIV-infected children

Author: Zhang, C ; Denti, P ; Simonsson, USH ; Maartens, Gary ; Karlsson, MO ; McIlleron, H Date: 2010 Children with HIV associated tuberculosis often require co-formulated lopinavir/ritonavir (LPV/RTV)-based antiretroviral treatment with rifampicin-based antitubercular treatment (ATT). Rifampicin (RIF), a potent inducer of drug-metabolizing ... Read more c b

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