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Browsing by Author "Selhorst, Philippe"

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Case report: mechanisms of HIV elite control in two African women

Author: Moosa, Yumna ; Tanko, Ramla F ; Ramsuran, Veron ; Singh, Ravesh ; Madzivhandila, Mashudu ; Yende-Zuma, Nonhlanhla ; Abrahams, Melissa-Rose ; Selhorst, Philippe ; Gounder, Kamini ; Moore, Penny L ; Williamson, Carolyn ; Abdool Karim, Salim S ; Garrett, Nigel J ; Burgers, Wendy A Date: 25 Jan 2018 Background: The majority of people living with HIV require antiretroviral therapy (ART) for controlling viral replication, however there are rare HIV controllers who spontaneously and durably control HIV in the absence of treatment. Understanding ... Read more c b
Characterisation of HIV-1 Envelope features of breakthrough infections from the CAPRISA 004 Microbicide Trial

Author: Ismail, Sherazaan Dineo Date: 2016 The CAPRISA 004 trial demonstrated the safety and a 39% efficacy of a 1% tenofovir (TFV) gel for the prevention of HIV-1 acquisition in young African women. It was subsequently shown that women assigned to the TFV arm who became infected had ... Read more
Detectable HIV-1 in semen in individuals with very low blood viral loads

Author: Kariuki, Samuel M ; Selhorst, Philippe ; Norman, Jennifer ; Cohen, Karen ; Rebe, Kevin ; Williamson, Carolyn ; Dorfman, Jeffrey R Date: 05 Mar 2020 Abstract Background Several reports indicate that a portion (5–10%) of men living with HIV-1 intermittently shed HIV-1 RNA into seminal plasma while on long term effective antiretroviral therapy (ART). This is highly suggestive of an HIV-1 ... Read more
The HIV‑1 transmission bottleneck

Author: Kariuki, Samuel Mundia ; Selhorst, Philippe ; Ariën, Kevin K ; Dorfman, Jeffrey Robert Date: 25 Mar 2017 It is well established that most new systemic infections of HIV-1 can be traced back to one or a limited number of founder viruses. Usually, these founders are more closely related to minor HIV-1 populations in the blood of the presumed donor ... Read more c b
The HIV-1 transmission bottleneck

Author: Kariuki, Samuel M ; Selhorst, Philippe ; Ariën, Kevin K ; Dorfman, Jeffrey R Date: 23 Mar 2017 It is well established that most new systemic infections of HIV-1 can be traced back to one or a limited number of founder viruses. Usually, these founders are more closely related to minor HIV-1 populations in the blood of the presumed donor ... Read more

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Browsing by Author "Selhorst, Philippe"

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