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Browsing by Author "Scott, Christiaan"

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A Retrospective Review of Paediatric Non-Infectious Uveitisin Cape Town: Disease Characteristics and Outcomes on Immunomodulating Treatment

Author: Slamang, Waheba Date: 2020 Background Uveitis is a known cause of blindness in the developed world, where non-infectious diseases dominate the spectrum of underlying aetiologies. However, data from sub-Saharan Africa is lacking. Here we aim to describe the diseases ... Read more
Adverse impact of hospitalisation on infant breastfeeding practices: a prospective cohort study

Author: Alisio, Michelle Date: 2019 Background: In South Africa, the exclusive breastfeeding prevalence at six months is low at 24% and the under-5 mortality rate remains high. Improving breastfeeding rates is the most cost-effective intervention to reduce under-5 mortality and ... Read more
Characteristics and outcome of children with juvenile dermatomyositis in Cape Town: a cross-sectional study

Author: Okong’o, Lawrence O ; Esser, Monika ; Wilmshurst, Jo ; Scott, Christiaan Date: 11 Nov 2016 Background: Juvenile dermatomyositis (JDM) is a rare idiopathic inflammatory childhood myopathy of uncertain aetiology. The demographic and clinical presentation of JDM may differ by race and geographic regions. Few studies have described the ... Read more c b
Demographic and clinical characteristics of children with juvenile dermatomyositis in Cape Town

Author: Okong'o, Lawrence Owino Date: 2015 Study rationale: Juvenile dermatomyositis (JDM) is a rare idiopathic inflammatory myopathy of childhood with an incidence of 1.9-3.2 per million. The aetiology of JDM is uncertain but may result from immune dysregulation triggered by environmental ... Read more
Establishing an international awareness day for paediatric rheumatic diseases: reflections from the inaugural World Young Rheumatic Diseases (WORD) Day 2019

Author: Smith, Eve M D ; Ainsworth, Sammy ; Beresford, Michael W ; Buys, Veerle ; Costello, Wendy ; Egert, Yona ; Foster, Helen E ; Lamot, Lovro ; Prakken, Berent J ; Scott, Christiaan ; Stones, Simon R Date: 11 Sep 2020 There is a lack of awareness of paediatric rheumatic diseases (PRDs), among the public, and certain groups of healthcare professionals (HCPs), including general practitioners. To help improve international awareness and understanding of PRDs, ... Read more
Juvenile idiopathic arthritis (JIA) in two tertiary centres in the Western Cape, South Africa

Author: Weakley, Kate ; Esser, Monika ; Pope, Chris ; Scott, Christiaan Date: 2011 Background: JIA is a disease that shows wide variations between differing populations. Due to recent international consensus on classification criteria, JIA has been widely described in many countries and population groups. There has been ... Read more c b
Juvenile idiopathic arthritis in two tertiary centres in the Western Cape, South Africa

Author: Weakley, Kate ; Esser, Monika ; Scott, Christiaan Date: 2012 BACKGROUND:Juvenile idiopathic arthritis (JIA) is a disease that shows wide variations between differing populations. Since the recent international consensus on classification criteria, JIA has been widely described in many countries and ... Read more c b
Missed opportunities for timely diagnosis of pediatric lupus in South Africa: a qualitative study

Author: Lewandowski, Laura B ; Watt, Melissa H ; Schanberg, Laura E ; Thielman, Nathan M ; Scott, Christiaan Date: 23 Feb 2017 Background: Systemic Lupus Erythematosus (SLE) is a serious multisystem autoimmune disease, which is more aggressive in children and people of African descent. In South Africa, pediatric SLE (pSLE) patients are at high risk for severe disease. ... Read more c b
MyastheniaGravis(MG) in a patient with Juvenile Idiopathic Arthritis

Author: Scott, Christiaan ; Kalla, Asgar Date: 2011 Introduction; Myasthenia Gravis associated with Juvenile Idiopathic Arthritis has been reported in 5children with various subtypes of JIA [1,2]. Methods: We present a 17year old girl known with Rheumatoid Factor Positive Polyarticular Juvenile ... Read more c b
Paediatric non-infectious uveitis in Cape Town, South Africa: a retrospective review of disease characteristics and outcomes on immunomodulating treatment

Author: Slamang, Waheba ; Tinley, Christopher ; Brice, Nicola ; Scott, Christiaan Date: 01 Apr 2021 Background Non-infectious uveitis is a well-reported cause of blindness in more developed countries, however data from sub-Saharan Africa is lacking. Here we aim to describe the diseases associated with paediatric non-infectious ... Read more c b
Pediatric rheumatology in Africa: thriving amidst challenges

Author: Migowa, Angela N ; Hadef, Djohra ; Hamdi, Wafa ; Mwizerwa, Oscar ; Ngandeu, Madeleine ; Taha, Yassmin ; Ayodele, Faleye ; Webb, Kate ; Scott, Christiaan Date: 07 May 2021 Abstract Background Pediatric Rheumatology is an orphan specialty in Africa which is gradually gaining importance across the continent. Main body ... Read more
Pediatric systemic lupus erythematosus patients in South Africa have high prevalence and severity of cardiac and vascular manifestations

Author: Harrison, Michael J ; Zühlke, Liesl J ; Lewandowski, Laura B ; Scott, Christiaan Date: 26 Nov 2019 Abstract Background Pediatric onset of systemic lupus erythematosus (SLE) is associated with major organ involvement, and African patients tend to develop more aggressive disease than patients ... Read more
Revising the WHO Essential Medicines List for paediatric rheumatology

Author: Scott, Christiaan ; Smith, Nicola ; James, Rebecca ; Whitehead, Ben ; Green, Rochelle ; Foster, Helen E Date: 23 Jan 2021 Read more c b
Serious adverse drug reactions at two children’s hospitals in South Africa

Author: Mouton, Johannes P ; Fortuin-de Smidt, Melony C ; Jobanputra, Nicole ; Mehta, Ushma ; Stewart, Annemie ; de Waal, Reneé ; Technau, Karl-Günter ; Argent, Andrew ; Kroon, Max ; Scott, Christiaan ; Cohen, Karen Date: 04 Jan 2020 Abstract Background The high HIV prevalence in South Africa may potentially be shaping the local adverse drug reaction (ADR) burden. We aimed to describe the prevalence and characteristics of serious ADRs at admission, and during admission, ... Read more
The paediatric global musculoskeletal task force - ‘towards better MSK health for all’

Author: Foster, Helen E ; Scott, Christiaan ; Tiderius, Carl J ; Dobbs, Matthew B Date: 14 Jul 2020 Abstract There is increasing concern about the emerging global non-communicable diseases (NCDs) burden. The focus has mainly been on NCDs in adults but it is important that MSK morbidity in both children and adults is included in strategic ... Read more

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