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Browsing by Author "Schwegmann, Anita"

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Identification of proteins that interact with brain factor-1 and characterization of these interactions

Author: Schwegmann, Anita Date: 2000 abstract Read more
IL-4Rα-Dependent Alternative Activation of Macrophages Is Not Decisive for Mycobacterium tuberculosis Pathology and Bacterial Burden in Mice

Author: Guler, Reto ; Parihar, Suraj P ; Savvi, Suzana ; Logan, Erin ; Schwegmann, Anita ; Roy, Sugata ; Nieuwenhuizen, Natalie E ; Ozturk, Mumin ; Schmeier, Sebastian ; Suzuki, Harukazu ; Brombacher, Frank Date: 2015 Classical activation of macrophages (caMph or M1) is crucial for host protection against Mycobacterium tuberculosis ( Mtb ) infection. Evidence suggests that IL-4/IL-13 alternatively activated macrophages (aaMph or M2) are exploited by Mtb ... Read more c b
IL-4Rα-independent expression of mannose receptor and Ym1 by macrophages depends on their IL-10 responsiveness

Author: Dewals, Benjamin G ; Marillier, Reece G ; Hoving, Jennifer C ; Leeto, Mosiuoa ; Schwegmann, Anita ; Brombacher, Frank Date: 2010 IL-4Rα-dependent responses are essential for granuloma formation and host survival during acute schistosomiasis. Previously, we demonstrated that mice deficient for macrophage-specific IL-4Rα (LysMcreIl4ra−/lox) developed increased hepatotoxicity ... Read more c b
OntoDas - a tool for facilitating the construction of complex queries to the Gene Ontology

Author: O'Neill, Kieran ; Garcia, Alexander ; Schwegmann, Anita ; Jimenez, Rafael ; Jacobson, Dan ; Hermjakob, Henning Date: 2008 BACKGROUND: Ontologies such as the Gene Ontology can enable the construction of complex queries over biological information in a conceptual way, however existing systems to do this are too technical. Within the biological domain there is an ... Read more c b
The role of B-cells and IgM antibodies in parasitemia, anemia, and VSG switching in Trypanosoma brucei-infected mice

Author: Magez, Stefan ; Schwegmann, Anita ; Atkinson, Robert ; Claes, Filip ; Drennan, Michael ; De Baetselier, Patrick ; Brombacher, Frank Date: 2008 Author Summary African trypanosomiasis is a disease caused by different species of extracellular flagellated protozoan trypanosome parasites. Trypanosomes have developed a mechanism of regular antigenic variation of their variant-specific ... Read more c b
The role of CD4+T cells in host protective responses against cutaneous Leishmaniasis using genome-wide transcriptomics.

Author: Smith, Liezel C Date: 2013 Leishmania major is a protozoan parasite and infection in the human host causes severe cutaneous Leishmaniasis. The study aims to determine how signaling via the IL-4Rα on CD4+T cells causes susceptibility to L. major. We compared gene ... Read more

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Browsing by Author "Schwegmann, Anita"

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