Browsing by Author "Schaaf, H Simon"

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Aminoglycoside-induced hearing loss: South Africans at risk

Author: Bardien, Soraya ; de Jong, Greetje ; Schaaf, H Simon ; Harris, Tashneem ; Fagan, Johan ; Petersen, Lucretia Date: 2009 South Africa is currently experiencing a TB epidemic with an estimated incidence of 940/100 000 population/year, and the country has been ranked 4th among the 22 high-burden TB countries worldwide by the World Health Organization (WHO). A ... Read more
Culture-confirmed childhood tuberculosis in Cape Town, South Africa: a review of 596 cases

Author: Schaaf, H Simon ; Marais, Ben ; Whitelaw, Andrew ; Hesseling, Anneke ; Eley, Brian ; Hussey, Gregory ; Donald, Peter Date: 2007 BACKGROUND:The clinical, radiological and microbiological features of culture-confirmed childhood tuberculosis diagnosed at two referral hospitals are described. METHODS: Cultures of Mycobacterium tuberculosis from children less than 13 years ... Read more c b
A rapid method for detection of five known mutations associated with aminoglycoside-induced deafness

Author: Bardien, Soraya ; Human, Hannique ; Harris, Tashneem ; Hefke, Gwynneth ; Veikondis, Rene ; Schaaf, H Simon ; van der Merwe, Lize ; Greinwald, John ; Fagan, Johan ; de Jong, Greetje Date: 2009 BACKGROUND:South Africa has one of the highest incidences of multidrug-resistant tuberculosis (MDR-TB) in the world. Concomitantly, aminoglycosides are commonly used in this country as a treatment against MDR-TB. To date, at least five mutations ... Read more c b

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