Browsing by Author "Rotherham, Lia S"

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HIV-1 subtype C unproductively infects human cardiomyocytes in vitro and induces apoptosis mitigated by an anti-gp120 aptamer

Author: de Campos, Walter R Lopes ; Chirwa, Nthato ; London, Grace ; Rotherham, Lia S ; Morris, Lynn ; Mayosi, Bongani M ; Khati, Makobetsa Date: 2014 HIV-associated cardiomyopathy (HIVCM) is of clinical concern in developing countries because of a high HIV-1 prevalence, especially subtype C, and limited access to highly active antiretroviral therapy (HAART). For these reasons, we investigated ... Read more c b
Selection and application of ssDNA aptamers to detect active TB from sputum samples

Author: Rotherham, Lia S ; Maserumule, Charlotte ; Dheda, Keertan ; Theron, Jacques ; Khati, Makobetsa Date: 2012 BACKGROUND: Despite the enormous global burden of tuberculosis (TB), conventional approaches to diagnosis continue to rely on tests that have major drawbacks. The improvement of TB diagnostics relies, not only on good biomarkers, but also ... Read more c b

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