Browsing by Author "Ren, Yuan"

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The Plasma, Whole Blood and Intracellular Concentrations of Antiretroviral Agents in South African Children Receiving Combination Antiretroviral Therapy with and without Concomitant Antitubercular Treatment

Author: Ren, Yuan Date: 2009 Background: Tuberculosis (TB) is the most common opportunistic infection in children with human immunodeficiency virus (HIV) infection in developing countries, and co-treatment for HIV infection and TB is frequently indicated. Efavirenz and ... Read more
PXR and CAR single nucleotide polymorphisms influence plasma efavirenz levels in South African HIV/AIDS patients

Author: Swart, Marelize ; Whitehorn, Heather ; Ren, Yuan ; Smith, Peter ; Ramesar, Rajkumar ; Dandara, Collet Date: 2012 BACKGROUND: This study investigated variation in NR1I2 and NR1I3 and its effect on plasma efavirenz levels in HIV/AIDS patients. Variability in plasma drug levels has largely led research on identifying causative variants in drug metabolising ... Read more c b

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