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Browsing by Author "Peter, Jonny"

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Comparison of same day diagnostic tools including Gene Xpert and unstimulated IFN-γ for the evaluation of pleural tuberculosis: a prospective cohort study

Author: Meldau, Richard ; Peter, Jonny ; Theron, Grant ; Calligaro, Greg ; Allwood, Brian ; Symons, Greg ; Khalfey, Hoosain ; Ntombenhle, Gina ; Govender, Ureshnie ; Binder, Anke ; van Zyl-Smit, Richard ; Dheda, Keertan Date: 08 Apr 2014 Background: The accuracy of currently available same-day diagnostic tools (smear microscopy and conventional nucleic acid amplification tests) for pleural tuberculosis (TB) is sub-optimal. Newer technologies may offer improved detection. ... Read more c b
Correlation of mycobacterium tuberculosis specific and non-specific quantitative Th1 T-cell responses with bacillary load in a high burden setting

Author: Theron, Grant ; Peter, Jonny ; Lenders, Laura ; van Zyl-Smit, Richard ; Meldau, Richard ; Govender, Ureshnie ; Dheda, Keertan Date: 2012 BACKGROUND: Measures of bacillary load in patients with tuberculosis (TB) may be useful for predicting and monitoring response to treatment. The relationship between quantitative T-cell responses and mycobacterial load remains unclear. We ... Read more c b
High frequency of resistance, lack of clinical benefit, and poor outcomes in capreomycin treated South african patients with extensively drug-resistant tuberculosis

Author: Pietersen, Elize ; Peter, Jonny ; Streicher, Elizabeth ; Sirgel, Frik ; Rockwood, Neesha ; Mastrapa, Barbara ; Te Riele, Julian ; Davids, Malika ; van Helden, Paul ; Warren, Robin ; Dheda, Keertan Date: 2015 BACKGROUND: There are limited data about the epidemiology and treatment-related outcomes associated with capreomycin resistance in patients with XDR-TB. Capreomycin achieves high serum concentrations relative to MIC but whether capreomycin ... Read more c b
Psychological distress and its relationship with non-adherence to TB treatment: a multicentre study

Author: Theron, Grant ; Peter, Jonny ; Zijenah, Lynn ; Chanda, Duncan ; Mangu, Chacha ; Clowes, Petra ; Rachow, Andrea ; Lesosky, Maia ; Hoelscher, Michael ; Pym, Alex ; Mwaba, Peter ; Mason, Peter ; Naidoo, Pamela ; Pooran, Anil ; Sohn, Hojoon ; Pai, Madhukar ; Stein, Dan Date: 2015 BACKGROUND:The successful cure of tuberculosis (TB) is dependent on adherence to treatment. Various factors influence adherence, however, few are easily modifiable. There are limited data regarding correlates of psychological distress and ... Read more c b
Test characteristics and potential impact of the urine LAM lateral flow assay in HIV-infected outpatients under investigation for TB and able to self-expectorate sputum for diagnostic testing

Author: Peter, Jonny ; Theron, Grant ; Chanda, Duncan ; Clowes, Petra ; Rachow, Andrea ; Lesosky, Maia ; Hoelscher, Michael ; Mwaba, Peter ; Pym, Alex ; Dheda, Keertan ; For the TB-NEAT team Date: 2015 BACKGROUND: The commercially available urine LAM strip test, a point-of-care tuberculosis (TB) assay, requires evaluation in a primary care setting where it is most needed. There is currently inadequate data to guide implementation in TB and ... Read more c b
The utility of a shortened palliative care screening tool to predict death within 12 months – a prospective observational study in two south African hospitals with a high HIV burden

Author: Raubenheimer, Peter J ; Day, Cascia ; Abdullah, Faried ; Manning, Katherine ; Cupido, Clint ; Peter, Jonny Date: 13 Nov 2019 Abstract Background Timely identification of people who are at risk of dying is an important first component of end-of-life care. Clinicians often fail to identify such patients, thus trigger tools have been developed to assist in this ... Read more

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Browsing by Author "Peter, Jonny"

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