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Browsing by Author "Peter, Jonathan"

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Clinical utility of a commercial LAM-ELISA assay for TB diagnosis in HIV-infected patients using urine and sputum samples

Author: Dheda, Keertan ; Davids, Virginia ; Lenders, Laura ; Roberts, Teri ; Meldau, Richard ; Ling, Daphne ; Brunet, Laurence ; Smit, Richard van Zyl ; Peter, Jonathan ; Green, Clare ; Badri, Motasim ; Sechi, Leonardo ; Sharma, Surendra ; Hoelscher, Michael ; Dawson, Rodney Date: 2010 BACKGROUND: The accurate diagnosis of TB in HIV-infected patients, particularly with advanced immunosuppression, is difficult. Recent studies indicate that a lipoarabinomannan (LAM) assay (Clearview-TB®-ELISA) may have some utility for the ... Read more c b
Comparison of quantitative techniques including Xpert MTB/RIF to evaluate mycobacterial burden

Author: van Zyl-Smit, Richard N ; Binder, Anke ; Meldau, Richard ; Mishra, Hridesh ; Semple, Patricia L ; Theron, Grant ; Peter, Jonathan ; Whitelaw, Andrew ; Sharma, Suren K ; Warren, Robin ; Bateman, Eric D ; Dheda, Keertan Date: 2011 Introduction: Accurate quantification of mycobacterial load is important for the evaluation of patient infectiousness, disease severity and monitoring treatment response in human and in-vitro laboratory models of disease. We hypothesized that ... Read more c b
Delirium amongst HIV-infected general medical admissions in Cape Town, South Africa

Author: Day, Cascia Date: 2021 Background Delirium is associated with increased mortality and hospital length of stay. Limited data are available from HIV-infected acute hospital admissions in developing countries. We conducted a prospective study of delirium amongst acute ... Read more
Determine TB-LAM lateral flow urine antigen assay for HIV-associated tuberculosis: recommendations on the design and reporting of clinical studies

Author: Lawn, Stephen ; Dheda, Keertan ; Kerkhoff, Andrew ; Peter, Jonathan ; Dorman, Susan ; Boehme, Catharina ; Nicol, Mark Date: 2013 Detection of the Mycobacterium tuberculosis cell wall antigen lipoarabinomannan (LAM) in urine permits diagnoses of tuberculosis (TB) to be made in HIV-infected patients with advanced immunodeficiency. This can be achieved at the point-of-care ... Read more c b
Development of a simple reliable radiographic scoring system to aid the diagnosis of pulmonary tuberculosis

Author: Pinto, Lancelot M ; Dheda, Keertan ; Theron, Grant ; Allwood, Brian ; Calligaro, Gregory ; van Zyl-Smit, Richard ; Peter, Jonathan ; Schwartzman, Kevin ; Menzies, Dick ; Bateman, Eric ; Pai, Madhukar ; Dawson, Rodney Date: 2013 Rationale: Chest radiography is sometimes the only method available for investigating patients with possible pulmonary tuberculosis (PTB) with negative sputum smears. However, interpretation of chest radiographs in this context lacks specificity ... Read more c b
Immunological evaluation of HIV-negative invasive fungal disease at Groote Schuur Hospital, Cape Town, South Africa

Author: Onyango, Vonwicks Czelestakov Date: 2019 Background The majority of invasive fungal disease in South African hospitals is HIV-related or associated with another secondary immunodeficiency e.g. haematopoietic stem cell transplant. After excluding secondary immunodeficiency, a detailed ... Read more
Immunoproteome of anti-TB drug associated DRESS in HIV TB co-infection

Author: Buck, Chloe Date: 2022 Introduction: A greater incidence of severe cutaneous adverse drug reaction (SCAR) such as Drug Reaction with Eosinophilia Systemic Symptoms (DRESS) occur among HIV-infected patients. We sought to characterize the immunoproteomic profile of ... Read more
Neuropsychological sequelae of paediatric posterior fossa brain tumours : the effect on quality of life

Author: Leng, Jeanette Anne Date: 2002 Bibliography: leaves 248-285. Read more
Prevalence and outcome of delirium amongst acute general medical inpatients in Cape Town, South Africa

Author: Du Plooy, Daniël Francois Date: 2019 Objectives Delirium is a common, serious, underdiagnosed condition in acute medical and surgical inpatients. It is associated with increased risk of mortality and morbidity. Data are largely limited to developed countries in geriatric ... Read more
Spinal compression in childhood : the University of Cape Town experience

Author: Buwembo, Joseph E Date: 1996 Aim: A retrospective study of cases of childhood spinal compression over a 30-year period (1963-1992) was undertaken in order to determine the trend in incidence, aetiology, diagnosis, treatment and prognosis. Patients and Methods: The study ... Read more
Utility of novel diagnostic tests for tuberculosis using human urine

Author: Muchinga, Tapuwa Enwell Date: 2012 Two thirds of new TB cases in sub-Saharan Africa are HIV coinfected. HIV-TB co-infection increases the incidence of extra-pulmonary, sputum smear-negative and sputum-scarce TB. In these vulnerable patientgroups with high mortality rates, ... Read more
Variations in pollen and fungal spore air spora: an analysis of 30 years of monitoring for the clinical assessment of patients in the Western Cape

Author: Berman, Dilys Melanie Date: 2018 Background and aims: Pollen and fungal spore concentrations in the atmosphere of Cape Town have been monitored since 1984 in two areas of Cape Town. Volumetric spore traps were used to monitor the air spora that trigger allergic disease in ... Read more

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