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Browsing by Author "Peres, Jade"

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The role of T-box transcription factor TBX3 in rhabdomyosarcoma

Author: Sims, Danica Anne Date: 2016 Cancer remains one of the leading causes of death worldwide due to late diagnosis and ineffective treatment options. To address this problem requires the elucidation of the molecular mechanisms, including the signaling pathways and transcription ... Read more
Studying the Role of Mechanical Properties of Cancer Cells in Tumour Detachment, Migration and Secondary Tumour Formation

Author: Higgins, Ghodeejah Date: 2021 Tumour cell detachment, migration and invasion, and secondary tumour formation are critical oncogenic processes during cancer metastasis. Although several molecular mechanisms have been reported to facilitate metastasis, it remains elusive ... Read more
The T-box transcription factor TBX3 drives proliferation by direct repression of the p21WAF1 cyclin-dependent kinase inhibitor

Author: Willmer, Tarryn ; Hare, Shannagh ; Peres, Jade ; Prince, Sharon Date: 22 Apr 2016 Background: TBX3, a member of the T-box family of transcription factors, is essential in development and has emerged as an important player in the oncogenic process. TBX3 is overexpressed in several cancers and has been shown to contribute ... Read more c b
The T-box transcription factor, TBX3, is sufficient to promote melanoma formation and invasion

Author: Peres, Jade ; Prince, Sharon Date: 2013 The T-box transcription factor, TBX3, is overexpressed in several cancers and has been proposed as a chemotherapeutic target. Several lines of evidence suggest that TBX3 may be a key contributor to malignant melanoma, a highly aggressive and ... Read more c b

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