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Browsing by Author "O'Ryan, Colleen"

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ASMT gene polymorphisms are associated with Autism Spectrum Disorder (ASD) symptom severity in a South African population

Author: De Waal, Margaretha Date: 2016 Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterised by behavioural and social impairments. ASD shows evidence of a genetic aetiology, with a large body of research linking ASD to polymorphisms in several different ... Read more
The biochemical analysis of southern African rhinoceros populations

Author: O'Ryan, Colleen Date: 1993 The drastic decline in the numbers of the five extant species of rhinoceroses world-wide, mainly as a result of poaching, have placed these species in imminent danger of extinction. This emphasizes the need to understand the relationships ... Read more
The characterization of MHC Class II genes of the Nile crocodile (Crocodylus niloticus) : an investigation of mechanisms that shape genetic diversity in natural populations

Author: Badenhorst, Lourie Date: 2008 Genes within the Major Histocompatibility Complex (MHC) of vertebrates code for proteins that are involved in antigen recognition and activation of the adaptive immune response. The hallmark of the MHC is the extremely high levels of polymorphism ... Read more
Cryptic Diversity of African Tigerfish (Genus Hydrocynus) Reveals Palaeogeographic Signatures of Linked Neogene Geotectonic Events

Author: Goodier, Sarah ; Cotterill, Fenton ; O'Ryan, Colleen ; Skelton, Paul ; de Wit, Maarten Date: 14 Dec 2011 The geobiotic history of landscapes can exhibit controls by tectonics over biotic evolution. This causal relationship positions ecologically specialized species as biotic indicators to decipher details of landscape evolution. Phylogeographic ... Read more c b
The development of the single-strand conformation polymorphism (SSCP) technique to assess sequence level variation within the major histocompatibility complex (MHC) DRB1 gene in four South African buffalo (Syncerus caffer) populations

Author: Hedley, Paula Date: 2003 This thesis reports the development of Single-Strand Conformation Polymorphism (SSCP) technique to assess sequence level variation within the Major Histocompatibility Complex (MHC) DRB1 gene in four South African buffalo populations. MHC gene ... Read more
Evolution of the African Tigerfish (Genus Hydrocynus) : phylogeographic insights into drainage evolution

Author: Goodier, Sarah Date: 2010 Aquatic species,notably fish, can reveal details of drainage evolution, especially where their evolutionary relationships can be reconstructed using phylogeographic methods. In this study, the mitochondrial DNA sequence diversity of the ... Read more
Genetic signatures for enhanced olfaction in the African mole-rats

Author: Stathopoulos, Sofia ; Bishop, Jacqueline M ; O'Ryan, Colleen Date: 2014 The Olfactory Receptor (OR) superfamily, the largest in the vertebrate genome, is responsible for vertebrate olfaction and is traditionally subdivided into 17 OR families. Recent studies characterising whole-OR subgenomes revealed a ‘birth ... Read more c b
Investigating genetic diversity at neutral and adaptive DNA markers in the severly bottlenecked Southern white Rhinoceros (Ceratotherium simum simum)

Author: Coutts, Natalie June Date: 2009 Read more
Investigation of DNA methylation at the promoter region of the aralkylamine N-acetyltransferase (AANAT ) gene in South African children with Autism Spectrum Disorder

Author: Van Wyk, Gerrit Date: 2017 Sleep problems and suppressed melatonin production commonly presents with core Autism Spectrum Disorder (ASD) traits. Aralkylamine N-acetyltransferase (AANAT) acts as the penultimate and rate-limiting enzyme in the melatonin biosynthetic ... Read more
An investigation of the sociogenetic structure of the endemic fynbos ant, Camponotus klugii, via the use of microsatellites

Author: Muna, Natashia Date: 2008 Eusocial insects, in particular ants, demonstrate great variability in their sociogenetic structure with regards to colony organization, queen number, queen mating frequency, levels of relatedness and worker reproduction. Within this study I ... Read more
Kinship and its consequences in the cooperatively breeding southern pied babbler Turdoides bicolor

Author: Nelson-Flower, Martha J Date: 2009 Cooperative breeding occurs when more than two individuals help to raise offspring that are not their own, and has been the focus of empirical and theoretical research for over forty years. Of central importance to this work are the fitness ... Read more
A macro- and micro-evolutionary investigation of African Camponotus ants

Author: Eick, Brigitte N Date: 2002 Camponotus than the cytochrome oxidase II gene, based on almost all measures of phylogenetic utility. The primary hypothesis proposed to account for this observation is that these two mitochondrial genes are evolving under different evolutionary ... Read more
A molecular perspective on the family Testudinidae batsch, 1788

Author: Cunningham, Jessica Date: 2002 The Family Testudinidae have a diverse distribution and, although limited to tropical and subtropical latitudes, are present on all continents with the exception of Australia and Antartica. Their evolutionary history dates back to the late ... Read more
Phylogeny and phylogeography of four southern ocean petrels

Author: Techow, N M S Mareile Date: 2007 This thesis investigates the phylogeography of four southern ocean petrel species in an attempt to resolve taxonomic uncertainties and phylogeography in these species. A large proportion of petrel and albatross species are listed as threatened ... Read more
Phylogeographic analysis reveals strong geographical structuring in the klipspringer, Oreotragus oreotragus

Author: Le Roex, Nikki Date: 2008 The klipspringer, Oreotragus oreotragus, occurs from the Western Cape of South Africa through to north-east Africa. Anthropological factors such as hunting have eradicated the klipspringer in parts of its former range and efforts have begun ... Read more
Quantification of genetic variation on Island-breeding populations of Procellariiformes : an assessment of the impact of the longline fishing industry on seabirds

Author: Kelso, Janet Date: 2000 The number of albatrosses that are killed on longlines in the Southern ocean is conservatively estimated to be 44 000 birds per annum. These numbers are biologically significant since albatrosses are a prime example of an extreme K-selected ... Read more
The serotonin transporter gene (SLC6A4) shows differential regulation between children with ASD and typically developing children in a South African population

Author: Hulley, Michaella Date: 2016 Autism spectrum disorders (ASD) are characterised by impairments in social interaction and communication, and repetitive and compulsive behaviours. The heterogeneous nature of ASD is underpinned by complex genetic networks; hence there is no ... Read more
Sociogenetic investigation of the southern harvester termite, Microhodotermes viator, via genetic and behavioural bioassays

Author: Muna, Natashia Date: 2014 This thesis presents the first investigation of the population structure of the southern harvester termite, Microhodotermes viator (Family: Hodotermitidae), by assessing the genetic state and behavioural interactions within and between twelve ... Read more
Studies of genetic, gastrointestinal, renal and dietary factors in white and black South African subjects as a possible key to understanding the relative absence of calcium oxalate kidney stone disease in the black population

Author: Theka, Takalani P Date: 2009 The incidence of urolithiasis in South Africa's black population is extremely rare «1%) while in the white population it is similar to that of western countries (-15%). The present thesis was aimed at shedding more light on the complex nature ... Read more
The tangled history of olfaction in African mole-rats, Bathyergidae: insights from Olfactory Receptor genes

Author: Stathopoulos, Sofia Date: 2012 This thesis reports the first assessment of OR variation in Bathyergidae, and therefore, the first for a family of subterranean mammals. Using a PCR-sequencing approach, 178 unique OR sequences, corresponding to 119 unique OR genes are ... Read more

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