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Browsing by Author "Noursadeghi, Mahdad"

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Cerebrospinal Fluid Cytokine Profiles Predict Risk of Early Mortality and Immune Reconstitution Inflammatory Syndrome in HIV-Associated Cryptococcal Meningitis

Author: Jarvis, Joseph N ; Meintjes, Graeme ; Bicanic, Tihana ; Buffa, Viviana ; Hogan, Louise ; Mo, Stephanie ; Tomlinson, Gillian ; Kropf, Pascale ; Noursadeghi, Mahdad ; Harrison, Thomas S Date: 2015 Author Summary Cryptococcal meningitis is a severe opportunistic infection, estimated to kill several hundred thousand HIV-infected individuals each year. One of the factors contributing to this high death toll is the inadequacy of antifungal ... Read more c b
In vivo molecular dissection of the effects of HIV-1 in active tuberculosis

Author: Bell, Lucy C K ; Pollara, Gabriele ; Pascoe, Mellissa ; Tomlinson, Gillian S ; Lehloenya, Rannakoe J ; Roe, Jennifer ; Meldau, Richard ; Miller, Robert F ; Ramsay, Alan ; Chain, Benjamin M ; Dheda, Keertan ; Noursadeghi, Mahdad Date: 2016 Author Summary HIV-1 infected people have substantially increased risk of tuberculosis (TB) leading to a large burden of disease worldwide. We aimed to investigate how HIV-1 causes this effect by altering human immune responses. We measured ... Read more c b

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