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Browsing by Author "Muloiwa, Rudzani"

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A systematic review of the epidemiology of hepatitis A in Africa

Author: Patterson, Jenna ; Abdullahi, Leila ; Hussey, Gregory D ; Muloiwa, Rudzani ; Kagina, Benjamin M Date: 22 Jul 2019 Abstract Background Hepatitis A, caused by the hepatitis A virus (HAV), is a vaccine preventable disease. In Low and Middle-Income Countries (LMICs), poor hygiene and sanitation conditions are ... Read more
An exploration of disclosure and non-disclosure patterns in HIV-infected children in Cape Town, South Africa

Author: Shea, Robert F Date: 2018 A cross-sectional, descriptive study combining with open-ended (qualitative) interview questions with quantitative component was conducted to explore disclosure experiences of mothers and caregivers of HIV-infected children. The study was ... Read more
Descriptive analysis of routine childhood immunisation timelines in the Western Cape, South Africa

Author: Blose, Ntombifuthi J Date: 2021 Background: Adherence to the recommended age-specific immunisation schedules is critical in ensuring vaccine effectiveness against vaccine preventable diseases (VPDs). Delays in the uptake of routine childhood immunisations lead to an increase ... Read more
Determinants of vaccine hesitancy in Africa: a systematic review

Author: Paone, Alexander Date: 2017 This MPH dissertation is a systematic review of the factors contributing to vaccine hesitancy in Africa. The dissertation comprises of the following three parts: The research protocol (Part A) outlines the background and proposed methods of ... Read more
Environmental and occupational respiratory diseases - 1040. Associations between asthma and bronchial hyper-responsivness with allergy and atopy phenotypes in urban black South African teenagers

Author: Levin, Michael ; Muloiwa, Rudzani ; Motala, Cassim Date: 2013 Epidemiological studies in South Africa show increasing prevalence rates of asthma and allergic sensitisation in both urban and rural Black African communities, and narrowing of the urban-rural gradient. There is a paucity of current data on ... Read more c b
Epidemiology of leptospirosis in Groote Schuur Hospital

Author: Mteshana, Ziningi Charity Date: 2021 Background The burden of leptospirosis in sub-Saharan Africa remains unclear although it is accepted that this infection is widely spread in this region. The global estimated number of cases is one million with 58 900 deaths attributable to ... Read more
Factors associated with increased mortality in a predominantly HIV-infected population with Stevens Johnson syndrome and toxic epidermal necrolysis

Author: Knight, Lauren ; Muloiwa, Rudzani ; Dlamini, Sipho ; Lehloenya, Rannakoe J Date: 2014 Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening drug reactions with a higher incidence in HIV-infected persons. SJS/TEN are associated with skin and mucosal failure, predisposing to systemic bacterial ... Read more c b
Incidence of anxiety and depression in a predominantly HIV-infected population with severe adverse drug reactions

Author: Zitha, Eddy ; Chiliza, Bonga ; Muloiwa, Rudzani ; Lehloenya, Rannakoe Date: 2014 Little is known on the short-term or medium-term psychological and psychiatric sequelae following Stevens Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and drug reaction with eosinophilia and systemic symptoms (DRESS). Based on ... Read more c b
Klebsiella pneumoniae bloodstream infections at a South African children’s hospital 2006–2011, a cross-sectional study

Author: Buys, Heloise ; Muloiwa, Rudzani ; Bamford, Colleen ; Eley, Brian Date: 17 Oct 2016 Background: Klebsiella pneumoniae (KP) is a significant paediatric bloodstream pathogen in children. There is little data from Africa. In this study we describe the epidemiology of multi-drug resistant Klebsiella pneumoniae bloodstream infection ... Read more c b
Laboratory findings that occur in Klebsiella pneumoniae blood stream infection in HIV-infected children compared to HIV uninfected children, at a South African children's hospital, Cape Town, 2006–2011: a nested-descriptive cross-sectional study

Author: Shapaka, Johanna Tekla Date: 2022 Background: Bloodstream infection (BSI) caused by Klebsiella pneumoniae (KP), is a leading cause of hospitalassociated childhood mortality. There are limited data on how poor outcomes of KPBSI can be predicted in poorly resourced areas. This ... Read more
Narcolepsy associated with Pandemrix influenza vaccine: A systematic review and meta-analysis

Author: Lakoma, Leif Date: 2021 This systematic review and meta-analysis forms the mini-dissertation part of the primarily coursework degree of Master of Public Health at the University of Cape Town. The review is divided into three separate parts. The first part constitutes ... Read more
Patterns of Detectable Viral Load in a cohort of HIV-infected adolescents on antiretroviral therapy

Author: Sher, Rebecca Yael Nthabiseng Date: 2018 Background Despite improved treatment and access to care, adolescent AIDS deaths are decreasing more slowly than in any other age group. There is lack of longitudinal data around adolescent adherence and the dynamics of viraemia over time. ... Read more
Patterns of mortality in children presenting to a tertiary paediatric emergency unit in Sub-Saharan Africa: a cross sectional study

Author: Josephs, Tracey Date: 2020 Background Pneumonia, diarrhoea and perinatal factors are the foremost killers of South African children as in other low- and middle-income countries. Poverty, poor access to care and pre-hospital care are reported major pre-hospital factors ... Read more
Pertussis outbreak in southern Ethiopia: challenges of detection, management, and response

Author: Mitiku, Aychiluhim D ; Argaw, Mesele D ; Desta, Binyam F ; Tsegaye, Zergu T ; Atsa, Afework A ; Tefera, Bekele B ; Teferi, Ephrem ; Rogers, Deirdre ; Beshir, Ismael A ; Alemu, Asrat G ; Ayesa, Desta A ; Abate, Derebe T ; Sendeku, Agegnehu G ; Muloiwa, Rudzani Date: 11 Aug 2020 Abstract Background Despite the availability of effective vaccines, pertussis remains endemic with high fatality rates in low and middle-income countries (LMIC). This study aims to describe an ... Read more
Prevalence of anxiety and depression in a predominantly HIV-infected population with severe cutaneous adverse drug reactions

Author: Zitha, Eddy Date: 2016 Background: There is limited data on anxiety and depression in subjects with severe cutaneous adverse drug reactions (SCADR), in a predominantly HIV - infected population. The aim of the study was to prospectively investigate the prevalence ... Read more
The prevalence of liquid chromatography-tandem mass spectrometry confirmed paediatric poisoning at Red Cross War Memorial Children’s Hospital, Cape Town, South Africa

Author: Washaya, Norbertta ; Evans, Alicia ; Muloiwa, Rudzani ; Smith, Peter ; Buys, Heloise Date: 18 Jan 2021 Background Paediatric poisoning is a common presentation to emergency departments worldwide. There is a paucity of data on the role of liquid chromatography-tandem mass spectrometry (LC-MS/MS), in the management of paediatric ... Read more c b
A retrospective review of the prevalence and management of anaemia in children in at Red Cross War Memorial Children's Hospital

Author: Wege, Martha Helena Date: 2015 Introduction Childhood anaemia is a major public health problem, iron deficiency being most common. WHO estimates anaemia to occur in 24.1% of pre-school South African children. Our study describes prevalence and management of anaemia in ... Read more
School based versus supplemental vaccination strategies in the delivery of vaccines to 5-19 year olds in Africa - a systematic review

Author: Haddison, Christiana Eposi Date: 2017 Background: Some vaccine preventable diseases still remain a public health burden in many African countries. The occurrence of vaccine preventable diseases in all age groups has led to the realization of the need to extend routine immunisation ... Read more
Stevens Johnson Syndrome and toxic epidermal necrolysis: maternal and foetal outcomes in twenty-two consecutive pregnant HIV infected women

Author: Knight, Lauren ; Todd, Gail ; Muloiwa, Rudzani ; Matjila, Mushi ; Lehloenya, Rannakoe J Date: 2015 Introduction Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) form a spectrum of a rare and life-threatening cutaneous drug reaction. SJS/TEN in pregnancy poses largely unknown risk factors and outcomes for both the mother ... Read more c b
The burden of human coronavirus infection in children hospitalized with severe lower respiratory tract infection in Cape Town, South Africa (2012-2013)

Author: Aliyu, Abdulmumuni Samuel Date: 2022 Introduction: In order to better understand the epidemiology and burden of human coronaviruses - NL63, HKU1, OC43 and 229E in South Africa, their role in the aetiology of childhood pneumonia needs to be described. Methods: We used data collected ... Read more

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