Browsing by Author "Menzel, Stephan"

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Identifying genetic variants and pathways associated with extreme levels of fetal hemoglobin in sickle cell disease in Tanzania

Author: Nkya, Siana ; Mwita, Liberata ; Mgaya, Josephine ; Kumburu, Happiness ; van Zwetselaar, Marco ; Menzel, Stephan ; Mazandu, Gaston K ; Sangeda, Raphael ; Chimusa, Emile ; Makani, Julie Date: 05 Jun 2020 Background Sickle cell disease (SCD) is a blood disorder caused by a point mutation on the beta globin gene resulting in the synthesis of abnormal hemoglobin. Fetal hemoglobin (HbF) reduces disease severity, but the levels vary from one ... Read more c b

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