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Browsing by Author "Meintjes, Ernesta M"

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4D flow and displacement sensitive MR imaging of upper arm arterio-venous connections for haemodialysis

Author: Jermy, Stephen Date: 2016 Chronic Kidney Disease (CKD) is a disease that causes kidney damage, often leading to the patient requiring haemodialysis treatment. Haemodialysis treatment requires a vascular access method, commonly Arteriovenous (AV) fistulae and grafts. ... Read more
Abnormal diastolic and systolic septal motion following pericardiectomy demonstrated by cine DENSE MRI

Author: Spottiswoode, Bruce ; Russell, James B ; Moosa, Sulaiman ; Meintjes, Ernesta M ; Epstein, Frederick H ; Mayosi, Bongani M Date: 2008 Constrictive pericarditis can lead to paradoxical interventricular septal motion. Displacement encoding with stimulated echoes (DENSE) magnetic resonance imaging (MRI) provides a method for quantifying myocardial motion and strain. A case of ... Read more
Comparison of resting state functional networks in HIV infected and uninfected children at age 9 years

Author: Stoltsz, Werner Heinrich Date: 2018 Over 2.5 million children are infected with HIV, the majority of whom reside in Sub-Saharan Africa. Treatment coverage is steadily gaining momentum, reducing mortality and morbidity. Yet little is known about brain development in HIV-infected ... Read more
Connectivity analysis of brain function in children with foetal alcohol spectrum disorder and control children during number processing

Author: Herron, Robyn Date: 2008 Maternal drinking during pregnancy is a significant problem in the Western Cape, South Africa, with an accompanying high incidence of children diagnosed with foetal alcohol spectrum disorder (FASD). Little is known about the neural correlates ... Read more
Development and validation of a quantitative choline food frequency questionnaire for use with drinking and non-drinking pregnant women in Cape Town, South Africa

Author: Carter, R Colin ; Jacobson, Sandra W ; Booley, Sharmilah ; Najaar, Baheya ; Dodge, Neil C ; Bechard, Lori J ; Meintjes, Ernesta M ; Molteno, Christopher D ; Duggan, Christopher P ; Jacobson, Joseph L ; Senekal, Marjanne Date: 22 Nov 2018 Background Although animal and human studies have demonstrated interactions between dietary choline and fetal alcohol spectrum disorders, dietary choline deficiency in pregnancy is common in the US and worldwide. We sought ... Read more
Development of a 3D radial MR Imaging sequence to be used for (self) navigation during the scanning of the fetal brain in utero

Author: Morgan, Leah Date: 2016 Imaging the fetal brain in utero is challenging due to the unpredictable motion of the fetus. Although ultra-fast MRI sequences are able to image a 2D slice in under a second, thus limiting the time in which fetal motion can corrupt images, ... Read more
Differences in resting state functional networks in HIV infected and uninfected children at age 7 years

Author: Toich, Jadrana Date: 2015 Although early administration of highly active antiretroviral therapy (HAART) in infants provides the brain some protection against HIV damage, few studies have examined the long-term effects of HIV infection and HAART on neurodevelopment, ... Read more
Diffusion tensor imaging point to ongoing functional impairment in HIV-infected children at age 5, undetectable using standard neurodevelopmental assessments

Author: Ackermann, Christelle ; Andronikou, Savvas ; Saleh, Muhammad G ; Kidd, Martin ; Cotton, Mark F ; Meintjes, Ernesta M ; Laughton, Barbara Date: 19 May 2020 Background Perinatal HIV infection negatively impacts cognitive functioning of children, main domains affected are working memory, processing speed and executive function. Early ART, even when interrupted, improves neurodevelopmental outcomes. ... Read more c b
Effects of HIV and different anti-retroviral therapy (ART) regimes on brain structure in HIV infected children at age 7

Author: Nwosu, Emmanuel Chukwubuikem Date: 2015 By 2013, more than 300, 000 children were living with HIV-infection in South Africa. The World Health Organization (WHO) recommended early aggressive antiretroviral therapy (ART) initiation to manage HIV in children, based on studies that ... Read more
The effects of HIV-1 infection on subcortical brain structures in children receiving ART : a structural MRI study

Author: Randall, Steven Ronald Date: 2015 INTRODUCTION This project investigated volumetric differences in certain subcortical structures as measured on high-resolution structural Magnetic Resonance Imaging (MRI) scans traced manually. The sample comprised 79 5-year old children, 52 ... Read more
Exploring the prevalence of developmental reading difficulties in Children with Fetal Alcohol Spectrum Disorders

Author: Bromley, Katie Rachael Date: 2009 Background. As part of a large ongoing research programme concerned with the teratogenic effects prenatal alcohol exposure has on the developing brain, this study investigated whether developmental reading difficulties are present in school-going ... Read more
Neural correlates of deficits in affect regulation in methamphetamine abusers with and without a history of psychosis

Author: Uhlmann, Anne Date: 2015 Methamphetamine dependence has been associated with neurological damage resulting in potentially long-lasting changes in cognitive-affective processes, a range of behavioral problems and psychiatric disorders, including psychosis. Poor emotional ... Read more
Neuroimaging and behavioral investigation of declarative memory in South African children prenatally exposed to alcohol

Author: Lewis, Catherine Elizabeth Date: 2018 Prenatal alcohol exposure (PAE) is associated with a range of physical, growth, and neurobehavioral deficits characteristic of individuals with fetal alcohol spectrum disorders (FASD). Although declarative memory impairment is a key feature ... Read more
Neuroimaging study of prenatal alcohol exposure effects on structural and functional connectivity in children

Author: Fan, Jia Date: 2015 Fetal alcohol spectrum disorders (FASD) describe the spectrum of cognitive, behavioural and neurological impairments associated with prenatal alcohol exposure (PAE). Diffusion tensor imaging (DTI) and resting-state functional MRI (rs-fMRI) ... Read more
The neurostructural effects of prenatal exposure to methamphetamine in an infant population in the Western Cape

Author: Warton, Fleur Louise Date: 2017 Prenatal methamphetamine exposure is associated with functional and neurostructural alterations, but neuroimaging investigations of these effects in infants are almost non-existent. Studies in neonates permit a degree of separation of drug ... Read more
Parietal dysfunction in children with prenatal alcohol exposure

Author: Woods, Keri Date: 2017 The parietal lobe has been shown to be one of the regions most affected by prenatal alcohol exposure. Functional domains dependent on intact parietal functioning, including mathematical and visuospatial ability, have been consistently implicated ... Read more
Quantifying right ventricular motion and strain using 3D cine DENSE MRI

Author: Auger, Daniel ; Zhong, Xiaodong ; Meintjes, Ernesta M ; Epstein, Frederick H ; Spottiswoode, Bruce S Date: 2011 Background: The RV is difficult to image because of its thin wall, asymmetric geometry and complex motion. DENSE is a quantitative MRI technique for measuring myocardial displacement and strain at high spatial and temporal resolutions [1,2]. ... Read more c b
Simultaneous DTI and rs-fMRI using the navigated diffusion sequence

Author: Mofya, Mwape Date: 2016 Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) experiments are normally performed separately. The idea of extracting inherently co-registered activation/connectivity ... Read more
A study of event-related electrocortical oscillatory dynamics associated with cued motor-response inhibition during performance of the Go/NoGo task within a sample of prenatally alcohol-exposed children and age-matched controls

Author: Gerhold, Mathew Michael Date: 2017 Fetal alcohol spectrum disorders (FASDs) are a spectrum of disorders that occur due to prenatal alcohol exposure (PAE). Response inhibition refers to the ability to inhibit/suppress a prepotent behavioural tendency set in motion during an ... Read more
A supervised machine-learning method for detecting steady-state visually evoked potentials for use in brain computer interfaces: A comparative assessment

Author: Duggan, Kieran Eamon Date: 2017 It is hypothesised that supervised machine learning on the estimated parameters output by a model for visually evoked potentials (VEPs), created by Kremlácek et al. (2002), could be used to classify steady-state visually evoked potentials ... Read more

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