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Browsing by Author "Meintjes, Ernesta"

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A vector based approach for high frequency prospective correction of rigid body motion in Magnetic Resonance Imaging (MRI)

Author: Van Niekerk, Adam Marthinus Johannes Date: 2019 Magnetic Resonance Imaging (MRI) is remarkable in that it is possible to obtain image resolutions much smaller than the wavelength of the radiated signal. This is achieved through the use of specialised gradient coils that linearly manipulate ... Read more
Active shape model segmentation of Brain structures in MR images of subjects with fetal alcohol spectrum disorder

Author: Eicher, Anton Date: 2010 Fetal Alcohol Spectrum Disorder (FASD) is the most common form of preventable mental retardation worldwide. This condition affects children whose mothers excessively consume alcohol whilst pregnant. FASD can be identified by physical and ... Read more
Assessing strain in arrhythmogenic right ventricular cardiomyopathy using cine DENSE MRI

Author: Ongori, Joash ; Hendricks, Neil ; Spottiswoode, Bruce ; Meintjes, Ernesta ; Epstein, Frederick ; Mayosi, Bongani Date: 2009 The kinematics of the right ventricle (RV) are not well understood due to its thin wall and asymmetric geometry. Cine displacement encoding with stimulated echoes (cine DENSE), which measures intramyocardial displacement and strain, has been ... Read more c b
Calculating 3D intramyocardial strain tensors in a single slice of myocardium using MRI

Author: Hess, Aaron Date: 2006 Strain is a measure of cardiac deformation and provides information on the mechanical and functional properties of the heart. As this deformation occurs in three dimensions (3D), a 3D measure of strain is appropriate, however, currently the ... Read more
Characterization of the facial phenotype associated with fetal alcohol syndrome using stereo-photogrammetry and geometric morphometrics

Author: Mutsvangwa, Tinashe E M Date: 2009 Fetal Alcohol Syndrome (FAS) is a clinical condition caused by excessive pre-natal alcohol exposure and is regarded as a leading identifiable and preventable cause of mental retardation in the Western world. The highest prevalence of FAS was ... Read more
Comparison of Magnetic Resonance Spectroscopy (MRS) data in children with and without HIV at 11-12 years

Author: Graham, Amy Date: 2020 Although HIV and antiretroviral drugs have been shown to cause damage in the brain, the long-term impacts of perinatal infection, early treatment and exposure in children at 11 years, remain unclear. The effects of HIV and antiretroviral ... Read more
A control system approach to subject specific prospective respiratory motion correction in cardiac MRI

Author: Burger, Ian H Date: 2012 Respiratory motion of the heart is a problem for high-resolution cardiac MRI. Diaphragmatic navigator gating with a 5mm acceptance window is most commonly used to address this but has an inherently low respiratory efficiency that is further ... Read more
Development of an interactive image-guided neurosurgical system

Author: Watson, Megan J Date: 2004 The aim of this project is to develop an interactive image-guided neurosurgical system. Three technologies for three-dimensional (3D) measurement were investigated and the method of choice developed. Read more
Differences in callosal and subcortical volumes and associated neurobehavioural deficits in children with prenatal alcohol exposure

Author: Biffen, Stevie Crystal Date: 2019 Certain high-risk communities in the Western Cape Province of South Africa where heavy maternal prenatal alcohol consumption is perpetuated by historical and societal challenges, have some of the highest prevalence rates of fetal alcohol ... Read more
DTI-based tractographic analysis of white matter alterations in HIV infected children

Author: Madzime, Joanah Date: 2019 Despite early combination antiretroviral therapy (cART) administration, children born with human immunodeficiency virus (HIV) continue to demonstrate neurodevelopmental abnormalities. Often, there is a link between structural and functional ... Read more
Effects of prenatal alcohol exposure on cerebellar volume in children an MRI study

Author: Boonzaier, Natalie Rosella Date: 2012 Years of research have demonstrated that prenatal exposure to alcohol contributes to a range of effects in exposed children. These include problems in attention and hyperactivity, deficits in memory and learning, and problems with social, as ... Read more
Elliptical Subject Specific model for respiratory motion

Author: Burger, Ian ; Meintjes, Ernesta ; Keegan, Jennifer ; Firmin, David Date: 2012 Respiratory motion of the heart poses a problem for high resolution cardiac MR imaging. Prospective slice following uses the navigator position immediately prior to the imaging segment to correct the slice positions throughout the segment ... Read more c b
Implementation of anatomical navigators for real time motion correction in diffusion tensor imaging

Author: Alhamud, Alkathafi Ali Date: 2012 Prospective motion correction methods using an optical system, diffusion-weighted prospective acquisition correction, or a free induction decay navigator have recently been applied to correct for motion in diffusion tensor imaging. These ... Read more
An investigation of the integrity of two components of the cerebellar neurocircuitry involved in classical eyeblink conditioning in children prenatally exposed to alcohol: a magnetic resonance spectroscopy and functional magnetic resonance imaging study

Author: Du Plessis, Lindie Date: 2014 Impairment in classical eyeblink conditioning (EBC) has previously been reported in children with fetal alcohol spectrum disorders (FASD) (Jacobson et al., 2008). The deep cerebellar nuclei and cerebellar cortex are critical elements of the ... Read more
Longitudinal analysis of Brain Metabolite levels for HIV infected Children from ages five to eleven

Author: Van Biljon, Noëlle Date: 2020 HIV infected (HIV+) children initiate antiretroviral therapy (ART) early in life and remain on it lifelong. However, the long-term impact of ART and HIV on the maturing brain is not well documented and longitudinal neuroimaging studies are ... Read more
Structural brain connectivity of HIV-positive children: a graph network analysis study

Author: Fouche,Jean-Paul Date: 2018 Vertical transmission of human immunodeficiency virus (HIV) from mother to child is a major problem in sub-Saharan Africa. As in adults, a variety of cognitive impairments may be evident in HIV infected children being treated with combined ... Read more
The impact of maternal HIV infection on uninfected neonate brain structure

Author: Ibrahim, Abdulmumin Date: 2022 Successful prevention of mother-to-child HIV transmission (PMTCT) programs have reduced the risk of infant HIV infection in South Africa from 8% in 2008 to an estimated 1.4% in 2015, resulting in an increasing population of HIV-exposed ... Read more
Tissue segmentation of the cerebellum from MR images

Author: Woods, Keri Date: 2011 The cerebellum is known to be very susceptible to prenatal exposure to alcohol and people affected by Fetal Alcohol Spectrum Disorder (FASD) show a decrease in cerebellar volume. Unfortunately, there seems to be little work that focuses ... Read more
Towards automating cine DENSE MRI image analysis : segmentation, tissue tracking and strain computation

Author: Spottiswoode, Bruce Shawn Date: 2006 Over the past two decades, magnetic resonance imaging (MRI) has developed into a powerful imaging tool for the heart. Imaging cardiac morphology is now commonplace in clinical practice, and a plethora of quantitative techniques have also ... Read more