OpenUCT Home
→
Browsing by Author

Browsing by Author "Meintjes, Ayton"

Now showing items 1-4 of 4

Accumulation of splice variants and transcripts in response to PI3K inhibition in T cells

Author: Riedel, Alice ; Mofolo, Boitumelo ; Avota, Elita ; Schneider-Schaulies, Sibylle ; Meintjes, Ayton ; Mulder, Nicola ; Kneitz, Susanne Date: 2013 BACKGROUND: Measles virus (MV) causes T cell suppression by interference with phosphatidylinositol-3-kinase (PI3K) activation. We previously found that this interference affected the activity of splice regulatory proteins and a T cell inhibitory ... Read more c b
Computational analysis of candidate disease genes and variants for salt-sensitive hypertension in indigenous Southern Africans

Author: Tiffin, Nicki ; Meintjes, Ayton ; Ramesar, Rajkumar ; Bajic, Vladimir B. ; Rayner, Brian Date: 2010 Multiple factors underlie susceptibility to essential hypertension, including a significant genetic and ethnic component, and environmental effects. Blood pressure response of hypertensive individuals to salt is heterogeneous, but salt ... Read more c b
Developing reproducible bioinformatics analysis workflows for heterogeneous computing environments to support African genomics

Author: Baichoo, Shakuntala ; Souilmi, Yassine ; Panji, Sumir ; Botha, Gerrit ; Meintjes, Ayton ; Hazelhurst, Scott ; Bendou, Hocine ; Beste, Eugene d ; Mpangase, Phelelani T ; Souiai, Oussema ; Alghali, Mustafa ; Yi, Long ; O’Connor, Brian D ; Crusoe, Michael ; Armstrong, Don ; Aron, Shaun ; Joubert, Fourie ; Ahmed, Azza E ; Mbiyavanga, Mamana ; Heusden, Peter v ; Magosi, Lerato E ; Zermeno, Jennie ; Mainzer, Liudmila S ; Fadlelmola, Faisal M ; Jongeneel, C. V ; Mulder, Nicola Date: 29 Nov 2018 Abstract Background The Pan-African bioinformatics network, H3ABioNet, comprises 27 research institutions in 17 African countries. H3ABioNet is part of the Human Health and Heredity in Africa ... Read more
A web-based protein interaction network visualizer

Author: Salazar, Gustavo A ; Meintjes, Ayton ; Mazandu, Gaston K ; Rapanoël, Holifidy A ; Akinola, Richard O ; Mulder, Nicola J Date: 06 May 2014 Abstract Background Interaction between proteins is one of the most important mechanisms in the execution of cellular functions. The study of these interactions has provided insight into the ... Read more c b

Now showing items 1-4 of 4

Browse

All of OpenUCT

Browsing by Author "Meintjes, Ayton"

Browsing by Author "Meintjes, Ayton"

Browse

All of OpenUCT