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Browsing by Author "Matsha, Tandi"

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Effects of diabetes mellitus on amyotrophic lateral sclerosis: a systematic review

Author: Lekoubou, Alain ; Matsha, Tandi ; Sobngwi, Eugene ; Kengne, Andre Date: 2014 BACKGROUND:Amyotrophic lateral sclerosis (ALS) is an incurable motor neuron degenerative disease which onset and course may be affected by concurrent diabetes mellitus (DM). We performed a systematic review to assess the effect of DM/dysglycemic ... Read more c b
Independent external validation and comparison of prevalent diabetes risk prediction models in a mixed-ancestry population of South Africa

Author: Masconi, Katya L ; Matsha, Tandi ; Erasmus, Rajiv ; Kengne, Andre Date: 2015 BACKGROUND: Guidelines increasingly encourage the use of multivariable risk models to predict the presence of prevalent undiagnosed type 2 diabetes mellitus worldwide. However, no single model can perform well in all settings and available ... Read more c b
Proliferator-activated receptor gamma Pro12Ala interacts with the insulin receptor substrate 1 Gly972Arg and increase the risk of insulin resistance and diabetes in the mixed ancestry population from South Africa

Author: Vergotine, Zelda ; Yako, Yandiswa ; Kengne, Andre ; Erasmus, Rajiv ; Matsha, Tandi Date: 2014 BACKGROUND: The peroxisome proliferator-activated receptor gamma (PPARG), Pro12Ala and the insulin receptor substrate (IRS1), Gly972Arg confer opposite effects on insulin resistance and type 2 diabetes mellitus (T2DM). We investigated the ... Read more c b
Reporting and handling of missing data in predictive research for prevalent undiagnosed type 2 diabetes mellitus: a systematic review

Author: Masconi, Katya L ; Matsha, Tandi ; Echouffo-Tcheugui, Justin ; Erasmus, Rajiv ; Kengne, Andre Date: 2015 Missing values are common in health research and omitting participants with missing data often leads to loss of statistical power, biased estimates and, consequently, inaccurate inferences. We critically reviewed the challenges posed by missing ... Read more c b
Validation of two prediction models of undiagnosed chronic kidney disease in mixed-ancestry South Africans

Author: Mogueo, Amelie ; Echouffo-Tcheugui, Justin ; Matsha, Tandi ; Erasmus, Rajiv ; Kengne, Andre Date: 2015 BACKGROUND: Chronic kidney disease (CKD) is a global challenge. Risk models to predict prevalent undiagnosed CKD have been published. However, none was developed or validated in an African population. We validated the Korean and Thai CKD ... Read more c b

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