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Browsing by Author "Makhema, Joseph"

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Features of recently transmitted HIV-1 clade C viruses that impact antibody recognition: implications for active and passive immunization

Author: Rademeyer, Cecilia ; Korber, Bette ; Seaman, Michael S ; Giorgi, Elena E ; Thebus, Ruwayhida ; Robles, Alexander ; Sheward, Daniel J ; Wagh, Kshitij ; Garrity, Jetta ; Carey, Brittany R ; Gao, Hongmei ; Greene, Kelli M ; Tang, Haili ; Bandawe, Gama P ; Marais, Jinny C ; Diphoko, Thabo E ; Hraber, Peter ; Tumba, Nancy ; Moore, Penny L ; Gray, Glenda E ; Kublin, James ; McElrath, M Juliana ; Vermeulen, Marion ; Middelkoop, Keren ; Bekker, Linda-Gail ; Hoelscher, Michael ; Maboko, Leonard ; Makhema, Joseph ; Robb, Merlin L ; Karim, Salim Abdool ; Karim, Quarraisha Abdool ; Kim, Jerome H ; Hahn, Beatrice H ; Gao, Feng ; Swanstrom, Ronald ; Morris, Lynn ; Montefiori, David C ; Williamson, Carolyn Date: 2016 Author Summary: Vaccine and passive immunization prophylactic trials that rely on antibody-mediated protection are planned for HIV-1 clade C epidemic regions of southern Africa, which have amongst the highest HIV-1 incidences globally. This ... Read more c b
Regional differences in prevalence of HIV-1 discordance in Africa and enrollment of HIV-1 discordant couples into an HIV-1 prevention trial

Author: Lingappa, Jairam R ; Lambdin, Barrot ; Bukusi, Elizabeth Ann ; Ngure, Kenneth ; Kavuma, Linda ; Inambao, Mubiana ; Kanweka, William ; Allen, Susan ; Kiarie, James N ; Makhema, Joseph Date: 2008 BACKGROUND: Most HIV-1 transmission in Africa occurs among HIV-1-discordant couples (one partner HIV-1 infected and one uninfected) who are unaware of their discordant HIV-1 serostatus. Given the high HIV-1 incidence among HIV-1 discordant ... Read more c b

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