Browsing by Author "Louw, Ann"

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Impact of glucocorticoid receptor density on ligand-independent dimerization, cooperative ligand-binding and basal priming of transactivation: a cell culture model

Author: Robertson, Steven ; Rohwer, Johann M ; Hapgood, Janet P ; Louw, Ann Date: 2013 Glucocorticoid receptor (GR) levels vary between tissues and individuals and are altered by physiological and pharmacological effectors. However, the effects and implications of differences in GR concentration have not been fully elucidated. ... Read more c b
Inhibition of corticosteroid-binding globulin gene expression by glucocorticoids involves C/EBPβ

Author: Verhoog, Nicolette ; Allie-Reid, Fatima ; Berghe, Wim Vanden ; Smith, Carine ; Haegeman, Guy ; Hapgood, Janet ; Louw, Ann Date: 2014 Corticosteroid-binding globulin (CBG), a negative acute phase protein produced primarily in the liver, is responsible for the transport of glucocorticoids (GCs). It also modulates the bioavailability of GCs, as only free or unbound steroids ... Read more c b

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