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Browsing by Author "Leal, Paulo C"

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SB225002 induces cell death and cell cycle arrest in acute lymphoblastic leukemia cells through the activation of GLIPR1

Author: De Vasconcellos, Jaíra Ferreira ; Laranjeira, Angelo Brunelli Albertoni ; Leal, Paulo C ; Bhasin, Manoj K ; Zenatti, Priscila Pini ; Nunes, Ricardo J ; Yunes, Rosendo A ; Nowill, Alexandre E ; Libermann, Towia A ; Zerbini, Luiz Fernando ; Yunes, José Andrés Date: 2015 Acute Lymphoblastic Leukemia (ALL) is the most frequent childhood malignancy. In the effort to find new anti-leukemic agents, we evaluated the small drug SB225002 (N-(2-hydroxy-4-nitrophenyl)-N'-(2-bromophenyl)urea). Although initially described ... Read more c b

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