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Browsing by Author "Klovrza, Ondrej"

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mTOR inhibitor improves autistic-like behaviors related to Tsc2 haploinsufficiency but not following developmental status epilepticus

Author: Petrasek, Tomas ; Vojtechova, Iveta ; Klovrza, Ondrej ; Tuckova, Klara ; Vejmola, Cestmir ; Rak, Jakub ; Sulakova, Anna ; Kaping, Daniel ; Bernhardt, Nadine ; de Vries, Petrus J ; Otahal, Jakub ; Waltereit, Robert Date: 17 Apr 2021 Abstract Background Tuberous sclerosis complex (TSC), a multi-system genetic disorder often associated with autism spectrum disorder (ASD), is caused by mutations of TSC1 or TSC2, which lead to ... Read more

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