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Efficacy of artemether-lumefantrine in relation to drug exposure in children with and without severe acute malnutrition: an open comparative intervention study in Mali and Niger

Author: Denoeud-Ndam, Lise ; Dicko, Alassane ; Baudin, Elisabeth ; Guindo, Ousmane ; Grandesso, Francesco ; Diawara, Halimatou ; Sissoko, Sibiri ; Sanogo, Koualy ; Traoré, Seydou ; Keita, Sekouba ; Barry, Amadou ; de Smet, Martin ; Lasry, Estrella ; Smit, Michiel ; Wiesner, Lubbe ; Barnes, Karen I ; Djimde, Abdoulaye A ; Guerin, Philippe J ; Grais, Rebecca F ; Doumbo, Ogobara K ; Etard, Jean-François Date: 24 Oct 2016 Background: Severe acute malnutrition (SAM) affects almost all organs and has been associated with reduced intestinal absorption of medicines. However, very limited information is available on the pharmacokinetic properties of antimalarial ... Read more c b

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