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Browsing by Author "Johnson, Leigh F"

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A multi-state model of treatment states in an antiretroviral treatment programme cohort in Cape Town

Author: Moolla, Haroon Date: 2022 Introduction A recent systematic review estimated that almost a quarter of patients in low- and middle-income countries are not retained on antiretroviral treatment (ART) beyond one year. Further, it is difficult to determine whether a patient ... Read more
A comparison of death recording by health centres and civil registration in South Africans receiving antiretroviral treatment

Author: Johnson, Leigh F ; Dorrington, Rob E ; Laubscher, Ria ; Hoffmann, Christopher J ; Wood, Robin ; Fox, Matthew P ; Cornell, Morna ; Schomaker, Michael ; Prozesky, Hans ; Tanser, Frank ; Davies, Mary-Ann ; Boulle, Andrew Date: 16 Dec 2015 Introduction: There is uncertainty regarding the completeness of death recording by civil registration and by health centres in South Africa. This paper aims to compare death recording by the two systems, in cohorts of South African patients ... Read more c b
Epidemiologic synergy - the contribution of heterosexual HIV transmission to the spread of HIV among men who have sex with men (MSM) in South Africa

Author: Mulongeni, Pancho Date: 2016 Background: Could heterosexual HIV transmission be a driver of HIV infections that occur in men who have sex with men (MSM)? Noting the disproportionately high HIV prevalence among MSM across a variety of settings, this subpopulation is often ... Read more
Estimation of adult antiretroviral treatment coverage in South Africa

Author: Adam, Muhammad Aarif ; Johnson, Leigh F Date: 2009 Objectives: To estimate the annual numbers of individuals receiving antiretroviral treatment in South Africa up to mid-2008, and the coverage of antiretroviral treatment in adults according to various definitions of need. Methods: Antiretroviral ... Read more c b n
Gender differences in survival among adult patients starting antiretroviral therapy in South Africa: a multicentre cohort study

Author: Cornell, Morna ; Schomaker, Michael ; Garone, Daniela Belen ; Giddy, Janet ; Hoffmann, Christopher J ; Lessells, Richard ; Maskew, Mhairi ; Prozesky, Hans ; Wood, Robin ; Johnson, Leigh F Date: 2012 Morna Cornell and colleagues investigate differences in mortality for HIV-positive men and women on antiretroviral therapy in South Africa. Read more c b
Impact of aetiological screening of sexually transmitted infections during pregnancy on pregnancy outcomes in South Africa

Author: Nyemba, Dorothy C. ; Peters, Remco P H ; Medina-Marino, Andrew ; Klausner, Jeffrey D ; Ngwepe, Phuti ; Myer, Landon ; Johnson, Leigh F ; Joseph Davey, Dvora L Date: 09 Mar 2022 Background Sexually transmitted infections (STIs) during pregnancy may increase the risk of adverse pregnancy outcomes. STI syndromic management is standard of care in South Africa but has its limitations. We evaluated the ... Read more c b
The interaction between HIV and other sexually transmitted infections in South Africa: a model-based evaluation

Author: Johnson, Leigh F Date: 2008 Sexually transmitted infections (STIs) have been shown to increase the probability of HIV transmission, but there remains much uncertainty regarding the role of STI treatment in HIV prevention. This thesis aims to develop a mathematical model ... Read more
An investigation into the extent of uncertainty surrounding estimates of the impact of HIV/AIDS in South Africa

Author: Johnson, Leigh F ; Dorrington, Rob E ; Matthews, Alan P Date: 2007 HIV / AIDS statistics have been the source of much controversy in South Africa, but often the extent of uncertainty around these estimates is ignored. There is need for an assessment of the range of uncertainty around often-quoted HIV / AIDS ... Read more c b
Monitoring of antiretroviral therapy and mortality in HIV programmes in Malawi, South Africa and Zambia: mathematical modelling study

Author: Estill, Janne ; Egger, Matthias ; Johnson, Leigh F ; Gsponer, Thomas ; Wandeler, Gilles ; Davies, Mary-Ann ; Boulle, Andrew ; Wood, Robin ; Garone, Daniela ; Stringer, Jeffrey S A Date: 2013 Objectives Mortality in patients starting antiretroviral therapy (ART) is higher in Malawi and Zambia than in South Africa. We examined whether different monitoring of ART (viral load [VL] in South Africa and CD4 count in Malawi and Zambia) ... Read more c b
Precarious transition: a mortality study of South African ex-miners

Author: Bloch, Kim ; Johnson, Leigh F ; Nkosi, Mlindeli ; Ehrlich, Rodney Date: 11 Jul 2018 Background Despite their burden of a triple epidemic of silicosis, tuberculosis and HIV infection, little is known about the mortality experience of miners from the South African mining industry once they leave employment. ... Read more
Steady growth in antiretroviral treatment provision by disease management and community treatment programmes

Author: Johnson, Leigh F ; McLeod, Heather D Date: 2007 Although access to highly active antiretroviral treatment (HAART) in the South African public health sector is closely monitored, much remains unknown regarding the numbers of HIV-positive individuals receiving HAART outside the public health ... Read more
The effect of educational attainment and other factors on HIV risk in South African women: results from antenatal surveillance, 2000-2005

Author: Johnson, Leigh F ; Dorrington, Rob E ; Bradshaw, Debbie ; du Plessis, Hendrika ; Makubalo, Lindiwe Date: 2009 Objectives: To assess the effect of educational attainment and other factors on the risk of HIV in pregnant South African women. Design: Repeated cross-sectional surveys. Methods: Pregnant women attending public antenatal clinics were tested ... Read more

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