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Browsing by Author "Jaffer, Mohamed A"

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A deletion and point mutation study of the human papillomavirus type 16 major capsid gene

Author: Varsani, Arvind ; Williamson, Anna-Lise ; Jaffer, Mohamed A ; Rybicki, Edward P Date: 2006 Recombinant human papillomavirus (HPV) virus-like particles (VLPs) made from the major capsid protein L1 are promising vaccine candidates for use as vaccines against genital and other HPV infections, and particularly against HPV-16. However, ... Read more
An investigation into the use of human papillomavirus type 16 virus-like particles as a delivery vector system for foreign proteins: N- and C-terminal fusion of GFP to the L1 and L2 capsid proteins

Author: Windram, Oliver P ; Weber, Brandon ; Jaffer, Mohamed A ; Rybicki, Edward P ; Shepherd, Dionne N ; Varsani, Arvind Date: 2008 Development of vaccine strategies against human papillomavirus (HPV), which causes cervical cancer, is a priority. We investigated the use of virus-like particles (VLPs) of the most prevalent type, HPV-16, as carriers of foreign proteins. ... Read more
A modeled structure of an aptamer-gp120 complex provides insight into the mechanism of HIV-1 neutralization

Author: Joubert, Marisa K ; Kinsley, Nichole ; Capovilla, Alexio ; Sewell, B Trevor ; Jaffer, Mohamed A ; Khati, Makobetsa Date: 2010 The HIV-1 envelope glycoprotein, gp120, is a key target for a class of drugs called entry inhibitors. Here we used molecular modeling to construct a three-dimensional model of an anti-gp120 RNA aptamer, B40t77, alone and in complex with gp120. ... Read more
Subcellular organization of N2-fixing nodules of cowpea (Vigna unguiculata) supplied with silicon.

Author: Nelwamondo, Azwianewi ; Jaffer, Mohamed A ; Dakora, Felix D Date: 2001 Provision of silicon (0, 0.048, 0.096, 0.24, 0.48, and 0.96 g/1) in the form of silicic acid (H4SiO4) to nodulated cowpea plants(Vignia unguiculata [L.] Walp.) grown in liquid culture resulted in considerable changes in the internal organization ... Read more

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Browsing by Author "Jaffer, Mohamed A"

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