Browsing by Author "Heyderman, Robert S"

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Impaired CD4 T cell memory response to Streptococcus pneumoniae precedes CD4 T cell depletion in HIV-infected Malawian adults

Author: Glennie, Sarah J ; Sepako, Enoch ; Mzinza, David ; Harawa, Visopo ; Miles, David J C ; Jambo, Kondwani C ; Gordon, Stephen B ; Williams, Neil A ; Heyderman, Robert S Date: 2011 Objective Invasive pneumococcal disease (IPD) is a leading cause of morbidity and mortality in HIV-infected African adults. CD4 T cell depletion may partially explain this high disease burden but those with relatively preserved T cell numbers ... Read more c b
Stavudine toxicity in adult longer-term ART patients in Blantyre, Malawi

Author: van Oosterhout, Joep J ; Mallewa, Jane ; Kaunda, Symon ; Chagoma, Newton ; Njalale, Yassin ; Kampira, Elizabeth ; Mukaka, Mavuto ; Heyderman, Robert S Date: 2012 BACKGROUND: Stavudine is an effective and inexpensive antiretroviral drug, but no longer recommended by WHO for first-line antiretroviral regimens in resource-limited settings due to toxicity concerns. Because of the high cost of alternative ... Read more c b

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