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Browsing by Author "Hanekom, Willem"

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Comparison of mantoux and tine tuberculin skin tests in BCG-vaccinated children investigated for tuberculosis

Author: Pan, Wenli ; Matizirofa, Lyness ; Workman, Lesley ; Hawkridge, Tony ; Hanekom, Willem ; Mahomed, Hassan ; Hussey, Gregory ; Hatherill, Mark Date: 2009 Background: Tuberculin skin tests (TSTs) are long-established screening methods for tuberculosis (TB). We aimed to compare agreement between the intradermal Mantoux and multipuncture percutaneous Tine methods and to quantify risk factors for ... Read more c b
Evaluation of the quality of informed consent in a vaccine field trial in a developing country setting

Author: Minnies, Deon ; Hawkridge, Tony ; Hanekom, Willem ; Ehrlich, Rodney ; London, Leslie ; Hussey, Greg Date: 2008 BACKGROUND:Informed consent is an ethical and legal requirement for research involving human participants. However, few studies have evaluated the process, particularly in Africa.Participants in a case control study designed to identify ... Read more c b
Investigations of mycobacteria-specific memoryy/effector T cell responses in HIV infected children receiving antiretroviral therapy

Author: Tena-Coki, Nontobeko Gwendoline Date: 2011 Human immunodeficiency virus (HIV) infected children are at greater risk of developing tuberculosis disease, and might benefit from vaccination with novel TB vaccines. However, little is known about the effect of HIV-infection on function and ... Read more
Isolation of Non-Tuberculous Mycobacteria in Children Investigated for Pulmonary Tuberculosis

Author: Hatherill, Mark ; Hawkridge, Tony ; Whitelaw, Andrew ; Tameris, Michele ; Mahomed, Hassan ; Moyo, Sizulu ; Hanekom, Willem ; Hussey, Gregory Date: 2006 Objective To evaluate the frequency and clinical significance of non-tuberculous mycobacteria (NTM) isolates among children investigated for pulmonary tuberculosis in a rural South African community. METHODS: Children were investigated for ... Read more c b
Transcriptional profiling of mycobacterial antigen-induced responses in infants vaccinated with BCG at birth

Author: Fletcher, Helen ; Keyser, Alana ; Bowmaker, Mark ; Sayles, Peter ; Kaplan, Gilla ; Hussey, Greg ; Hill, Adrian ; Hanekom, Willem Date: 2009 BACKGROUND:Novel tuberculosis (TB) vaccines recently tested in humans have been designed to boost immunity induced by the current vaccine, Mycobacterium bovis Bacille Calmette-Guerin (BCG). Because BCG vaccination is used extensively in ... Read more c b

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Browsing by Author "Hanekom, Willem"

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