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Browsing by Author "Gamieldien, Hoyam"

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Comparing high-throughput methods to measure antibody dependent cellular cytotoxicity during HIV infection

Author: Mbodo, Iyaloo Date: 2014 The prevalence of HIV-1 is highest in Sub-Saharan Africa. Protective immune responses directed against HIV are complex and involve both cellular and humoral immunity. Based on the recent finding that the best correlate of protection against ... Read more
Evolution of HIV-1 subtype C immune responses during acute and chronic HIV infection

Author: Gamieldien, Hoyam Date: 2011 The aim of this study was to compare the magnitude and breadth of HIV-specific T cell responses to HIV Gag and Nef mounted during acute HIV infection with those that emerged during chronic infection and to investigate the association of these ... Read more
In Silico Characterisation of Putative Prophages in Lactobacillaceae Used in Probiotics for Vaginal Health

Author: Happel, Anna-Ursula ; Kullin, Brian R ; Gamieldien, Hoyam ; Jaspan, Heather B ; Varsani, Arvind ; Martin, Darren ; Passmore, Jo-Ann S ; Froissart, Rémy Date: 20 Jan 2022 While live biotherapeutics offer a promising approach to optimizing vaginal microbiota, the presence of functional prophages within introduced Lactobacillaceae strains could impact their safety and efficacy. We evaluated the presence of ... Read more c b
Isolation and Characterization of Bacteriophages Targeting Uropathogenic E. coli

Author: Magwai, Thandi Date: 2019 Urinary tract infections (UTI)are one of the most common human bacterial infections, caused by uropathogenic E. coli (UPEC). Conventionally, UTI’s are treated with antibiotics, such as sulpha-mathoxazole/trimethoprim and ampicillin. However, ... Read more
Microbial function and genital inflammation in young South African women at high risk of HIV infection

Author: Alisoltani, Arghavan ; Manhanzva, Monalisa T ; Potgieter, Matthys ; Balle, Christina ; Bell, Liam ; Ross, Elizabeth ; Iranzadeh, Arash ; du Plessis, Michelle ; Radzey, Nina ; McDonald, Zac ; Calder, Bridget ; Allali, Imane ; Mulder, Nicola ; Dabee, Smritee ; Barnabas, Shaun ; Gamieldien, Hoyam ; Godzik, Adam ; Blackburn, Jonathan M ; Tabb, David L ; Bekker, Linda-Gail ; Jaspan, Heather B ; Passmore, Jo-Ann S ; Masson, Lindi Date: 21 Nov 2020 Abstract Background Female genital tract (FGT) inflammation is an important risk factor for HIV acquisition. The FGT microbiome is closely associated with inflammatory profile; however, the relative importance of microbial activities has ... Read more

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Browsing by Author "Gamieldien, Hoyam"

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