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Browsing by Author "Fick, Lizette"

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A cross-reactive monoclonal antibody to nematode haemoglobin enhances protective immune responses to Nippostrongylus brasiliensis

Author: Nieuwenhuizen, Natalie E ; Meter, Jeanne M ; Horsnell, William G ; Hoving, J Claire ; Fick, Lizette ; Sharp, Michael F ; Darby, Matthew G ; Parihar, Suraj P ; Brombacher, Frank ; Lopata, Andreas L Date: 2013 Background: Nematode secreted haemoglobins have unusually high affinity for oxygen and possess nitric oxide deoxygenase, and catalase activity thought to be important in protection against host immune responses to infection. In this study, ... Read more c b
IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis

Author: Gasse, Paméla ; Riteau, Nicolas ; Vacher, Rachel ; Michel, Marie-Laure ; Fautrel, Alain ; di Padova, Franco ; Fick, Lizette ; Charron, Sabine ; Lagente, Vincent ; Eberl, Gérard Date: 2011 BACKGROUND: Idiopathic pulmonary fibrosis is a devastating as yet untreatable disease. We demonstrated recently the predominant role of the NLRP3 inflammasome activation and IL-1β expression in the establishment of pulmonary inflammation and ... Read more c b
IL-4/IL-13 independent goblet cell hyperplasia in experimental helminth infections

Author: Marillier, Reece ; Michels, Chesney ; Smith, Elizabeth ; Fick, Lizette ; Leeto, Mosiuoa ; Dewals, Benjamin ; Horsnell, William ; Brombacher, Frank Date: 2008 BACKGROUND: Intestinal mucus production by hyperplasic goblet cells is a striking pathological feature of many parasitic helminth infections and is related to intestinal protection and worm expulsion. Induction of goblet cell hyperplasia is ... Read more c b
Reactivation of M. tuberculosis infection in trans-membrane tumour necrosis factor mice

Author: Dambuza, Ivy ; Keeton, Roanne ; Allie, Nasiema ; Hsu, Nai-Jen ; Randall, Philippa ; Sebesho, Boipelo ; Fick, Lizette ; Quesniaux, Valerie J F ; Jacobs, Muazzam Date: 2011 Of those individuals who are infected with M. tuberculosis , 90% do not develop active disease and represents a large reservoir of M. tuberculosis with the potential for reactivation of infection. Sustained TNF expression is required for ... Read more c b

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Browsing by Author "Fick, Lizette"

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