Browsing by Author "Ferreira, Roux-cil"

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Chinks in the armor of the HIV-1 Envelope glycan shield: implications for immune escape from anti-glycan broadly neutralizing antibodies

Author: Moyo, Thandeka ; Ferreira, Roux-cil ; Davids, Reyaaz ; Sonday, Zarinah ; Moore, Penny L ; Travers, Simon A ; Wood, Natasha T ; Dorfman, Jeffrey Robert Date: 15 Jan 2017 Glycans on HIV-1 Envelope serve multiple functions including blocking epitopes from antibodies. We show that removal of glycan 301, a major target of anti-V3/glycan antibodies, has substantially different effects in two viruses. While glycan ... Read more

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