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Intra-and inter-clade cross-reactivity by HIV-1 Gag specific T-cells reveals exclusive and commonly targeted regions: implications for current vaccine trials

Author: Zembe, Lycias ; Burgers, Wendy A ; Jaspan, Heather B ; Bekker, Linda-Gail ; Bredell, Helba ; Stevens, Gwynneth ; Gilmour, Jill ; Cox, Josephine H ; Fast, Patricia ; Hayes, Peter Date: 2011 The genetic diversity of HIV-1 across the globe is a major challenge for developing an HIV vaccine. To facilitate immunogen design, it is important to characterize clusters of commonly targeted T-cell epitopes across different HIV clades. To ... Read more c b

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