Author:Barth, Dylan DominicDate:2018BACKGROUND AND AIMS OF THE THESIS: Group A β-haemolytic Streptococcus (GAS) also known as Streptococcus pyogenes, is responsible for a wide range of invasive and non-invasive GAS diseases. Prevalence and incidence data on GAS from developing ...Read more
Author:Watkins, David; Sebitloane, Motshedisi; Engel, Mark E; Mayosi, BonganiDate:2012BACKGROUND: Maternal mortality in South Africa is rising, and heart conditions currently account for 41 per cent of indirect causes of deaths. Little is known about the burden of heart disease in pregnant South Africans. METHODS: We systematically ...Read morecb
Author:Wasserman, Sean; Engel, Mark E; Griesel, Rulan; Mendelson, MarcDate:09 Sep 2016Abstract
Background
Seroprevalence data and clinical studies in children suggest that the burden of pneumocystis pneumonia (PCP) in Africa may be underestimated. We performed a systematic ...Read more
Author:Wasserman, Sean; Engel, Mark E; Mendelson, MarcDate:2013BACKGROUND: Reports from Africa have suggested that pneumocystis pneumonia (PCP) is a less important cause of morbidity than in the developed world. However, more recent studies have shown high seroprevalence rates of P. jirovecii in healthy ...Read morecb
Author:Atkins, Salla; Lewin, Simon; Smith, Helen; Engel, Mark E; Fretheim, Atle; Volmink, JimmyDate:2008BACKGROUND:Qualitative synthesis has become more commonplace in recent years. Meta-ethnography is one of several methods for synthesising qualitative research and is being used increasingly within health care research. However, many aspects ...Read morecb
Author:Fong, Francisco JDate:2019PART A is a research protocol which describes the background and proposed methodology of this systematic review and meta-analysis. This section details the quantitative and qualitative methods to be used when analysing the effect of Aloe in ...Read more
Author:Ford, NathanDate:2009Highly active antiretroviral therapy (HAART) has dramatically affected the course of HIV disease, resulting in a significant reduction in AIDS-related morbidity and mortality in both developed and developing countries.Read more
Author:Barth, Dylan DominicDate:2013Part A: is the research protocol which outlines the background and the process of this research. This study is a population-based observational study nested within the Groote Schuur Hospital (GSH) cohort of a global study, REMEDY which is a ...Read more
Author:Naidoo, Lionel EdmundDate:2010We conducted a systematic review and meta-analysis of randomised and quasi-randomised trials to determine the effectiveness of community-based rehabilitation versus hospital/institution based rehabilitation in providing rehabilitative services ...Read more
Author:Schmidt, Bey-Marrié; Engel, Mark E; Abdullahi, Leila; Ehrlich, RodneyDate:25 May 2018Background
A number of guideline documents have been published over the past decades on preventing occupational transmission of tuberculosis (TB) infection in health care workers (HCWs). However, direct evidence for the ...Read more
Author:Mnguni, Ayanda Trevor; Engel, Mark E; Borkum, Megan S; Mayosi, Bongani MDate:2015BACKGROUND: Tuberculous pericardial effusion is a pro-fibrotic condition that is complicated by constrictive pericarditis in 4% to 8% of cases. N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) is a ubiquitous tetrapeptide with anti-fibrotic ...Read morecb
Author:Mnguni, Ayanda TrevorDate:2015Background: Tuberculous pericardial effusion is a pro-fibrotic condition that is complicated by constrictive pericarditis in 4-8% of cases. N-acetyl-seryl-aspartyl-lysylproline (Ac-SDKP) is a ubiquitous tetrapeptide with antifibrotic properties ...Read more
Author:Hohlfeld, Ameer Steven-JörgDate:2016Background: A leading research priority worldwide is the need to improve the lives of those with disabilities through the effective development of interventions that can be carried out by non-specialists. Recent research has indicated that ...Read more
Author:Eltayeb, DalyaDate:2016This MPH dissertation undertakes a systematic review on factors associated with patient and health system delay in diagnosing and commencing treatment for pulmonary tuberculosis in Middle East and North Africa (MENA). The dissertation is ...Read more
Author:Ramsey, Laura; Watkins, Lauren; Engel, Mark EDate:2013BACKGROUND:There is a significant global health burden associated with acute rheumatic fever (ARF) and rheumatic heart disease (RHD), especially in developing countries. ARF and RHD most often strike children and young adults living in ...Read morecb
Author:Abrams, JessicaDate:2018Part A is a research protocol which describes the background and proposed methodology of this systematic review. This section contains the details of quantitative and qualitative methods to be used when analysing rheumatic heart disease (RHD) ...Read more