Author:Vermaak, John-RandelDate:2019Background
Sub-Saharan Africa, the epicenter of the global population of people living with HIV (PLHIV), is estimated to have more than 25 million PLHIV. In the era before the widespread availability of antiretroviral therapy (ART), anaemia ...Read more
Author:Decloedt, EricDate:2010This article aims to highlight current trends in the pharmacologic management of obsessive–compulsive disorder (OCD). A systematic search of the electronic database MEDLINE was conducted. The first case report of clomipramine efficacy in the ...Read more
Author:Decloedt, Eric; Leisegang, Rory; Blockman, Marc; Cohen, KarenDate:2010BACKGROUND: Many drugs are eliminated by the kidneys and therefore may require dose adjustment in patients with renal impairment. The need for dose adjustment is frequently neglected by prescribers. METHODS: We reviewed folders of patients ...Read more
Author:Lesosky, Maia; Joska, John; Decloedt, EricDate:07 Jun 2017Background: Therapeutic drug monitoring (TDM) is essential practice when dosing drugs with a narrow therapeutic index in order to achieve a plasma drug concentration within a narrow target range above the efficacy concentration but below the ...Read more