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Browsing by Author "Cox, Helen"

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“A very humiliating illness”: a qualitative study of patient-centered Care for Rifampicin-Resistant Tuberculosis in South Africa

Author: Furin, Jennifer ; Loveday, Marian ; Hlangu, Sindisiwe ; Dickson-Hall, Lindy ; le Roux, Sacha ; Nicol, Mark ; Cox, Helen Date: 17 Jan 2020 Abstract Background Patient-centered care is pillar 1 of the “End TB” strategy, but little has been documented in the literature about what this means for people living with rifampicin-resistant (RR-TB). Optimizing care for such individuals ... Read more
Barriers to implementation of Tuberculosis infection control amongst South African Health Care Workers

Author: Adeleke, Oluwatoyin Date: 2012 HIV co-infection and drug resistance worsen the burden of Tuberculosis in South Africa. Infectious TB cases, often undiagnosed and untreated, are commonly found in health facilities increasing the likelihood of health-care associated TB. ... Read more
Baseline prevalence and incidence and risk factors for new-onset drug induced hearing loss in adults receiving drug-resistant tuberculosis (DR-TB) treatment in Khayelitsha, South Africa

Author: Njuguna, Christine Wanjiku Date: 2013 Treatment for drug-resistant tuberculosis (DR-TB) is longer and associated with more significant side-effects than drug susceptible TB. Second line injectable therapy using kanamycin, amikacin or capreomycin is associated with irreversible ... Read more
Clinical deterioration during antituberculosis treatment in Africa: Incidence, causes and risk factors

Author: Pepper, Dominique ; Marais, Suzaan ; Wilkinson, Robert ; Bhaijee, Feriyl ; Maartens, Gary ; McIlleron, Helen ; De Azevedo, Virginia ; Cox, Helen ; McDermid, Cheryl ; Sokhela, Simiso ; Patel, Janisha ; Meintjes, Graeme Date: 2010 BACKGROUND:HIV-1 and Mycobacterium tuberculosis cause substantial morbidity and mortality. Despite the availability of antiretroviral and antituberculosis treatment in Africa, clinical deterioration during antituberculosis treatment remains ... Read more c b
Conceptualising the right to enjoy benefits of scientific progress and exploring its potential to enhance access to effective diagnosis and treatment of drug-resistant tuberculosis in South Africa

Author: Shawa, Remmy Malama Date: 2019 The lack of access to effective diagnosis and treatment of drug-resistant tuberculosis (DR-TB) remains a persistent global challenge. Human rights arguments for access to treatment mostly focus on the right to health. However, a key challenge ... Read more
Population Structure of Mixed Mycobacterium tuberculosis Infection Is Strain Genotype and Culture Medium Dependent

Author: Hanekom, Madeleine ; Streicher, Elizabeth M ; Van de Berg, Doreen ; Cox, Helen ; McDermid, Cheryl ; Bosman, Marlein ; van Pittius, Nicolaas C Gey ; Victor, Tommie C ; Kidd, Martin ; van Soolingen, Dick Date: 2013 BACKGROUND: Molecular genotyping methods have shown infection with more than one Mycobacterium tuberculosis strain genotype in a single sputum culture, indicating mixed infection. Aim This study aimed to develop a PCR-based genotyping tool ... Read more c b
Rifampicin-resistant tuberculosis in Botswana: barriers and risk factors influencing patient outcomes, case detection, and linkage to effective care and treatment

Author: Boyd, Rosanna M Date: 2019 Background: Botswana reports high treatment success for rifampicin-resistant tuberculosis (RR-TB), but many challenges remain. Case detection is lower than expected and varies by year, and mortality rates are high. Research aims included ... Read more
The Epidemiology and Evolution of Rifampicin Mono Resistant Tuberculosis in Khayelitsha, Cape Town, South Africa

Author: Salaam-Dreyer, Zubeida Date: 2021 Background: According to the World Health Organization Global TB report 2018, rifampicin monoresistant tuberculosis (RMR-TB) comprises 22% and 38% of all rifampicin-resistant TB (RR-TB) globally, and within South Africa, respectively. National ... Read more
Whole genome sequencing reveals complex evolution patterns of multidrug-resistant Mycobacterium tuberculosis Beijing strains in patients

Author: Merker, Matthias ; Kohl, Thomas A ; Roetzer, Andreas ; Truebe, Leona ; Richter, Elvira ; Rüsch-Gerdes, Sabine ; Fattorini, Lanfranco ; Oggioni, Marco R ; Cox, Helen ; Varaine, Francis Date: 2013 Multidrug-resistant (MDR) Mycobacterium tuberculosis complex (MTBC) strains represent a major threat for tuberculosis (TB) control. Treatment of MDR-TB patients is long and less effective, resulting in a significant number of treatment failures. ... Read more c b
Wind-driven roof turbines: a novel way to improve ventilation for TB infection control in health facilities

Author: Cox, Helen ; Escombe, Rod ; McDermid, Cheryl ; Mtshemla, Yolanda ; Spelman, Tim ; Azevedo, Virginia ; London, Leslie Date: 2012 Objective Tuberculosis transmission in healthcare facilities contributes significantly to the TB epidemic, particularly in high HIV settings. Although improving ventilation may reduce transmission, there is a lack of evidence to support ... Read more c b

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Browsing by Author "Cox, Helen"

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