OpenUCT Home
→
Browsing by Author

Browsing by Author "Cotton, Mark"

Now showing items 1-9 of 9

Adherence to isoniazid prophylaxis among HIV-infected children: a randomized controlled trial comparing two dosing schedules

Author: le Roux, Stanzi ; Cotton, Mark ; Golub, Jonathan ; le Roux, David ; Workman, Lesley ; Zar, Heather Date: 2009 BACKGROUND:Tuberculosis contributes significantly to morbidity and mortality among HIV-infected children in sub-Saharan Africa. Isoniazid prophylaxis can reduce tuberculosis incidence in this population. However, for the treatment to be ... Read more c b
Early Antiretroviral Therapy reduces the incidence of otorrhea in a randomized study of early and deferred antiretroviral therapy: Evidence from the Children with HIV Early Antiretroviral Therapy (CHER) Study

Author: Hainline, Clotilde ; Taliep, Reghana ; Sorour, Gill ; Nachman, Sharon ; Rabie, Helena ; Dobbels, Els ; van Rensburg, Anita ; Cornell, Morna ; Violari, Avy ; Madhi, Shabir ; Cotton, Mark Date: 2011 BACKGROUND: Although otorrhea occurs commonly in HIV-infected infants, there are few data. We compared the incidence of otorrhea in infants receiving early vs deferred ART in the Children with HIV Early Antiretroviral (CHER) trial. Infants ... Read more c b
Emergence of a peak in early infant mortality due to HIV/AIDS in South Africa

Author: Bourne, David E ; Thompson, MaryLou ; Brodya, Linnea L ; Cotton, Mark ; Draper, Beverly ; Laubscher, Ria ; Abdullah, M Fareed ; Myers, Jonny E Date: 2009 Objectives: South Africa has among the highest levels of HIV prevalence in the world. Our objectives are to describe the distribution of South African infant and child mortality by age at fine resolution, to identify any trends over recent ... Read more
High incidence of antimicrobial resistant organisms including extended spectrum beta-lactamase producing Enterobacteriaceae and methicillin-resistant Staphylococcus aureus in nasopharyngeal and blood isolates of HIV-infected children from Cape Town, South Africa

Author: Cotton, Mark ; Wasserman, Elizabeth ; Smit, Juanita ; Whitelaw, Andrew ; Zar, Heather Date: 2008 BACKGROUND:There is little information on nasopharyngeal (NP) flora or bacteremia in HIV-infected children. Our aim was to describe the organisms and antimicrobial resistance patterns in children enrolled in a prospective study comparing daily ... Read more c b
It is time to consider third-line options in antiretroviral-experienced paediatric patients?

Author: van Zyl, Gert ; Rabie, Helena ; Nuttall, James ; Cotton, Mark Date: 2011 BACKGROUND: The historic use of full-dose ritonavir as part of an unboosted protease inhibitor (PI)-based antiretroviral therapy regimen in some South African children contributes to the frequent accumulation of major PI resistance mutations. ... Read more c b
Paediatric HIV disclosure in South Africa - caregivers' perspectives on discussing HIV with infected children

Author: Moodley, Keymanthri ; Myer, Landon ; Michaels, Desiree ; Cotton, Mark Date: 2006 Most paediatric HIV infections in South Africa are transmitted perinatally. Lack of widely available HIV treatment means that most children do not survive to an age at which disclosure becomes a relevant concern. However, with the expansion ... Read more
Shorter treatment for minimal tuberculosis (TB) in children (SHINE): a study protocol for a randomised controlled trial

Author: Chabala, Chishala ; Turkova, Anna ; Thomason, Margaret J ; Wobudeya, Eric ; Hissar, Syed ; Mave, Vidya ; van der Zalm, Marieke ; Palmer, Megan ; Kapasa, Monica ; Bhavani, Perumal K ; Balaji, Sarath ; Raichur, Priyanka A ; Demers, Anne-Marie ; Hoddinott, Graeme ; Owen-Powell, Ellen ; Kinikar, Aarti ; Musoke, Philippa ; Mulenga, Veronica ; Aarnoutse, Rob ; McIlleron, Helen ; Hesseling, Anneke ; Crook, Angela M ; Cotton, Mark ; Gibb, Diana M Date: 19 Apr 2018 Background: Tuberculosis (TB) in children is frequently paucibacillary and non-severe forms of pulmonary TB are common. Evidence for tuberculosis treatment in children is largely extrapolated from adult studies. Trials in adults with ... Read more
Spectrum, progression and predictors of morbidity in perinatally HIV-infected adolescents on antiretroviral therapy

Author: Frigati, Lisa Jane Date: 2021 Background: Long term survival of children living with HIV due to improved early access to antiretroviral therapy (ART) is contributing to a growing population of adolescents living with perinatally acquired HIV (PHIV+) at risk of developing ... Read more
Utility of clinical parameters to identify HIV infection in infants below ten weeks of age in South Africa: a prospective cohort study

Author: Jaspan, Heather ; Myer, Landon ; Madhi, Shabir ; Violari, Avy ; Gibb, Diana ; Stevens, Wendy ; Dobbels, Els ; Cotton, Mark Date: 2011 BACKGROUND:As HIV-infected infants have high mortality, the World Health Organization now recommends initiating antiretroviral therapy as early as possible in the first year of life. However, in many settings, laboratory diagnosis of HIV in ... Read more c b

Now showing items 1-9 of 9

Browse

All of OpenUCT

Browsing by Author "Cotton, Mark"

Browsing by Author "Cotton, Mark"

Browse

All of OpenUCT