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Browsing by Author "Burgers, Wendy A"

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Case report: mechanisms of HIV elite control in two African women

Author: Moosa, Yumna ; Tanko, Ramla F ; Ramsuran, Veron ; Singh, Ravesh ; Madzivhandila, Mashudu ; Yende-Zuma, Nonhlanhla ; Abrahams, Melissa-Rose ; Selhorst, Philippe ; Gounder, Kamini ; Moore, Penny L ; Williamson, Carolyn ; Abdool Karim, Salim S ; Garrett, Nigel J ; Burgers, Wendy A Date: 25 Jan 2018 Background: The majority of people living with HIV require antiretroviral therapy (ART) for controlling viral replication, however there are rare HIV controllers who spontaneously and durably control HIV in the absence of treatment. Understanding ... Read more c b
Characterization of Mycobacterium tuberculosis-specific Th22 cells in HIV-TB co-infection

Author: Makatsa, Mohau Steven Date: 2020 Tuberculosis (TB) remains the infectious disease causing the greatest global mortality, with an estimated 10 million incident cases of TB and 1.45 million deaths in 2018. Although there is a cure for TB, the success of the treatment is hampered ... Read more
Characterizing the cellular latent reservoir of HIV-1 and the effect of immune activation on characteristics of the reservoir

Author: Ismail, Sherazaan Dineo Date: 2022 Since the advent of antiretroviral therapy (ART) and the resultant suppression of viraemia in the majority of people living with HIV-1 (PLWH) on ART, HIV-1 infection has become manageable and PLWH have similar life expectancies as uninfected ... Read more
Intra-and inter-clade cross-reactivity by HIV-1 Gag specific T-cells reveals exclusive and commonly targeted regions: implications for current vaccine trials

Author: Zembe, Lycias ; Burgers, Wendy A ; Jaspan, Heather B ; Bekker, Linda-Gail ; Bredell, Helba ; Stevens, Gwynneth ; Gilmour, Jill ; Cox, Josephine H ; Fast, Patricia ; Hayes, Peter Date: 2011 The genetic diversity of HIV-1 across the globe is a major challenge for developing an HIV vaccine. To facilitate immunogen design, it is important to characterize clusters of commonly targeted T-cell epitopes across different HIV clades. To ... Read more c b
Investigating cytokine responses to different strains of Mycobacterium tuberculosis

Author: Booi, Zandile Date: 2021 Mycobacterium tuberculosis (Mtb), the causative agent of human tuberculosis (TB), is one of the world's most prevalent fatal pathogens, infecting one third of the global population. The highly specialised pathogen that infects humans today ... Read more
Restoration of cellular immunity in HIV-infected individuals on antiretroviral therapy

Author: Fatime Ramla, Tanko Date: 2017 During the course of HIV pathogenesis, the virus induces multiple defects in immune cells, altering their functional ability to efficiently control HIV itself and other infections. Whilst the widespread implementation of antiretroviral therapy ... Read more
SARS-CoV-2 Infection Is Associated with Uncontrolled HIV Viral Load in Non-Hospitalized HIV-Infected Patients from Gugulethu, South Africa

Author: Lambarey, Humaira ; Blumenthal, Melissa J ; Chetram, Abeen ; Joyimbana, Wendy ; Jennings, Lauren ; Tincho, Marius B ; Burgers, Wendy A ; Orrell, Catherine ; Schäfer, Georgia Date: 03 Jun 2022 In South Africa, high exposure to SARS-CoV-2 occurs primarily in densely populated, low-income communities, which are additionally burdened by highly prevalent Human Immunodeficiency Virus (HIV). With the aim to assess SARS-CoV-2 seroprevalence ... Read more c b

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Browsing by Author "Burgers, Wendy A"

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