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Browsing by Author "Balle, Christina"

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Effects of hormonal contraceptives on the female genital tract microbiota in South African adolescents

Author: Balle, Christina Date: 2018 Background Young women in sub-Saharan Africa are disproportionally affected by HIV and often rely on injectable hormonal contraception (HC) to prevent unintended pregnancies. However, HC might affect HIV-1 risk through changes in the female ... Read more
Microbial function and genital inflammation in young South African women at high risk of HIV infection

Author: Alisoltani, Arghavan ; Manhanzva, Monalisa T ; Potgieter, Matthys ; Balle, Christina ; Bell, Liam ; Ross, Elizabeth ; Iranzadeh, Arash ; du Plessis, Michelle ; Radzey, Nina ; McDonald, Zac ; Calder, Bridget ; Allali, Imane ; Mulder, Nicola ; Dabee, Smritee ; Barnabas, Shaun ; Gamieldien, Hoyam ; Godzik, Adam ; Blackburn, Jonathan M ; Tabb, David L ; Bekker, Linda-Gail ; Jaspan, Heather B ; Passmore, Jo-Ann S ; Masson, Lindi Date: 21 Nov 2020 Abstract Background Female genital tract (FGT) inflammation is an important risk factor for HIV acquisition. The FGT microbiome is closely associated with inflammatory profile; however, the relative importance of microbial activities has ... Read more
Presence and Persistence of Putative Lytic and Temperate Bacteriophages in Vaginal Metagenomes from South African Adolescents

Author: Happel, Anna-Ursula ; Balle, Christina ; Maust, Brandon S ; Konstantinus, Iyaloo N ; Gill, Katherine ; Bekker, Linda-Gail ; Froissart, Rémy ; Passmore, Jo-Ann ; Karaoz, Ulas ; Varsani, Arvind ; Jaspan, Heather Date: 23 Nov 2021 The interaction between gut bacterial and viral microbiota is thought to be important in human health. While fluctuations in female genital tract (FGT) bacterial microbiota similarly determine sexual health, little is known about the presence, ... Read more c b
The association between the oral and vaginal microbiome of young South African women

Author: Esra, Rachel Date: 2019 Bacterial vaginosis (BV) and periodontal disease (PD) are conditions characterised by reduction of healthy bacterial communities in the vaginal and oral microbiomes respectively. Both BV and PD are associated with an increased risk of preterm ... Read more

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