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Browsing by Author "Allie, Nasiema"

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Membrane TNF confers protection to acute mycobacterial infection

Author: Fremond, Cecile ; Allie, Nasiema ; Dambuza, Ivy M ; Grivennikov, Sergei ; Yeremeev, Vladimir ; Quesniaux, Valerie ; Jacobs, Muazzam ; Ryffel, Bernhard Date: 2005 BACKGROUND:Tumour necrosis factor (TNF) is crucial for the control of mycobacterial infection as TNF deficient (KO) die rapidly of uncontrolled infection with necrotic pneumonia. Here we investigated the role of membrane TNF for host resistance ... Read more c b
Reactivation of M. tuberculosis infection in trans-membrane tumour necrosis factor mice

Author: Dambuza, Ivy ; Keeton, Roanne ; Allie, Nasiema ; Hsu, Nai-Jen ; Randall, Philippa ; Sebesho, Boipelo ; Fick, Lizette ; Quesniaux, Valerie J F ; Jacobs, Muazzam Date: 2011 Of those individuals who are infected with M. tuberculosis , 90% do not develop active disease and represents a large reservoir of M. tuberculosis with the potential for reactivation of infection. Sustained TNF expression is required for ... Read more c b
TNF-dependent regulation and activation of innate immune cells are essential for host protection against cerebral tuberculosis

Author: Francisco, Ngiambudulu ; Hsu, Nai-Jen ; Keeton, Roanne ; Randall, Philippa ; Sebesho, Boipelo ; Allie, Nasiema ; Govender, Dhirendra ; Quesniaux, Valerie ; Ryffel, Bernhard ; Kellaway, Lauriston ; Jacobs, Muazzam Date: 2015 BACKGROUND: Tuberculosis (TB) affects one third of the global population, and TB of the central nervous system (CNS-TB) is the most severe form of tuberculosis which often associates with high mortality. The pro-inflammatory cytokine tumour ... Read more c b

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Browsing by Author "Allie, Nasiema"

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