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Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in noncardiac surgery

Author: Marcucci, Maura ; Painter, Thomas W ; Conen, David ; Leslie, Kate ; Lomivorotov, Vladimir V ; Sessler, Daniel ; Chan, Matthew T V ; Borges, Flavia K ; Martínez Zapata, Maria J ; Wang, C Y ; Xavier, Denis ; Ofori, Sandra N ; Landoni, Giovanni ; Efremov, Sergey ; Kleinlugtenbelt, Ydo V ; Szczeklik, Wojciech ; Schmartz, Denis ; Garg, Amit X ; Short, Timothy G ; Wittmann, Maria ; Meyhoff, Christian S ; Amir, Mohammed ; Torres, David ; Patel, Ameen ; Duceppe, Emmanuelle ; Ruetzler, Kurtz ; Parlow, Joel L ; Tandon, Vikas ; Wang, Michael K ; Fleischmann, Edith ; Polanczyk, Carisi A ; Jayaram, Raja ; Astrakov, Sergey V ; Rao, Mangala ; VanHelder, Tomas ; Wu, William K K ; Cheong, Chao C ; Ayad, Sabry ; Abubakirov, Marat ; Kirov, Mikhail ; Bhatt, Keyur ; de Nadal, Miriam ; Likhvantsev, Valery ; Iglesisas, Pilar P ; Aguado, Hector J ; McGillion, Michael ; Lamy, Andre ; Whitlock, Richard P. ; Roshanov, Pavel ; Stillo, David ; Copland, Ingrid ; Vincent, Jessica ; Balasubramanian, Kumar ; Bangdiwala, Shrikant I ; Biccard, Bruce ; Kurz, Andrea ; Srinathan, Sadeesh ; Petit, Shirley ; Eikelboom, John ; Richards, Toby ; Gross, Peter L ; Alfonsi, Pascal ; Guyatt, Gordon ; Belley-Cote, Emily ; Spence, Jessica ; McIntyre, William ; Yusuf, Salim ; Devereaux, P J Date: 31 Jan 2022 Background For patients undergoing noncardiac surgery, bleeding and hypotension are frequent and associated with increased mortality and cardiovascular complications. Tranexamic acid (TXA) is an antifibrinolytic agent with ... Read more c b

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Browsing by Author "fb1731e7-adf4-473f-a5e2-f75674c207ae"

Browsing by Author "fb1731e7-adf4-473f-a5e2-f75674c207ae"

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