OpenUCT :: Browsing by Author "Woodman, Z"

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Open Access
Beneficial HLA-mediated viral polymorphisms on the transmitted virus additively influence disease progression in HIV-1, subtype C infection
(BioMed Central Ltd, 2012) Ntale, R S; Chopera, D R; Ngandu, N K; Abrahams, M; Debra, A; Mlotswa, M; Werner, L; Woodman, Z; Mlisana, K; Karim, S; Gray, CM; Williamson, C; CAPRISA 002 AI Study Team
Transmitted viral factors have been shown to affect disease progression but whether infection with viruses carrying beneficial HLA-mediated escape polymorphisms affects disease progression in HLA-mismatched participants remains controversial.
Open Access
Characterization of envelope function of transmitted viruses circulating in Mbeya, Tanzania, and its impact on disease progression
(BioMed Central Ltd, 2012) Nofemela, A; Bandawe, G; Thebus, R; Marais, J; Maboko, L; Hoelscher, M; Williamson, C; Woodman, Z
An understanding of the biological characteristics of transmitted viruses provides important insights into HIV pathogenesis and informs vaccine development. The aim of the study was to characterize env function of transmitted viruses and its role in disease progression.