Browsing by Author "Whibley, Catherine"

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    Anti-oesophageal cancer activity in extracts of deep-water Marion Island sponges
    (2005) Davies-Coleman, Michael T; Froneman, William; Keyzers, Robert; Whibley, Catherine; Hendricks, Denver; Samaai, Toufiek; McQuaid, Christopher
    OESOPHAGEAL CANCER IS ONE OF THE most common causes of cancer-related deaths in South African black males. The limited efficacy of chemotherapeutic agents to treat this disease has prompted a search for potential new chemical entities with anticancer properties. We report here on the evidence for anti-oesophageal cancer activity in the methanolic extracts of five species of sponges dredged from a depth of approximately 100 m in the vicinity of Marion Island in the Southern Ocean during the autumn of 2004.