Browsing by Author "Singh, Vedantha"

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    An investigation of memory T cell phenotypes in peripheral blood of Chacma baboons after immunisation with candidate HIV-1 vaccines
    (2013) Singh, Vedantha; Chege, Gerald; Williamson, Anna-Lise
    Previous studies from the HIV Vaccine Development Group at the University of Cape Town have reported that immunisation with recombinant modified vaccinia Ankara (SAAVI MVA-C) or DNA prime and Pr55 Gag virus-like particle (VLP) boost based on HIV-1 subtype C are able to successfully induce vaccine specific responses in Chacma baboons. The aim of the current study was to characterise the T cell memory phenotype distribution in peripheral mononuclear cells (PBMCs) isolated from Chacma baboons vaccinated with SAAVI MVA-C/VLP and DNA/VLP prime-boost vaccination regimens by flow cytometry.