Browsing by Author "Simpson, John"

Now showing 1 - 7 of 7
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    Competencies, capabilities, and relational factors in buyer-supplier Business-to-Business networks
    (2012) Human, Gert Johannes Pretorius; Simpson, John
    Most of today's knowledge of Business-to-Business marketing is grounded on studies conducted in so-called western countries. Recently some researchers have started to question the validity of concepts, ideas and measures conceived in developed markets to explain business marketing phenomena in non-western contexts. Moreover research has attributed this gap in the literature on the relative absence of Business-to-Business marketing research from emerging, non-western countries (see, for example, Biggemann and Fam, 2011.) In emerging markets firms also operate in large networks that contains multiple, complex, direct and indirect business relationships among buyers and sellers. The thesis draws on four different empirical studies to integrate key sets of knowledge spawned from the realms of the Industrial Marketing and Purchasing group (IMP) to observe Business-to-Business relationships in a South African context.
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    Epidemic levels of drug resistant tuberculosis (MDR and XDR-TB) in a high HIV prevalence setting in Khayelitsha, South Africa
    (Public Library of Science, 2010) Cox, Helen S; McDermid, Cheryl; Azevedo, Virginia; Muller, Odelia; Coetzee, David; Simpson, John; Barnard, Marinus; Coetzee, Gerrit; van Cutsem, Gilles; Goemaere, Eric
    BACKGROUND: Although multidrug-resistant tuberculosis (MDR-TB) is emerging as a significant threat to tuberculosis control in high HIV prevalence countries such as South Africa, limited data is available on the burden of drug resistant tuberculosis and any association with HIV in such settings. We conducted a community-based representative survey to assess the MDR-TB burden in Khayelitsha, an urban township in South Africa with high HIV and TB prevalence. METHODOLOGY/PRINCIPAL FINDINGS: A cross-sectional survey was conducted among adult clinic attendees suspected for pulmonary tuberculosis in two large primary care clinics, together constituting 50% of the tuberculosis burden in Khayelitsha. Drug susceptibility testing (DST) for isoniazid and rifampicin was conducted using a line probe assay on positive sputum cultures, and with culture-based DST for first and second-line drugs. Between May and November 2008, culture positive pulmonary tuberculosis was diagnosed in 271 new and 264 previously treated tuberculosis suspects (sample enriched with previously treated cases). Among those with known HIV status, 55% and 71% were HIV infected respectively. MDR-TB was diagnosed in 3.3% and 7.7% of new and previously treated cases. These figures equate to an estimated case notification rate for MDR-TB of 51/100,000/year, with new cases constituting 55% of the estimated MDR-TB burden. HIV infection was not significantly associated with rifampicin resistance in multivariate analyses. Conclusions/Significance There is an extremely high burden of MDR-TB in this setting, most likely representing ongoing transmission. These data highlight the need to diagnose drug resistance among all TB cases, and for innovative models of case detection and treatment for MDR-TB, in order to interrupt transmission and control this emerging epidemic.
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    Impact of Xpert MTB/RIF for TB diagnosis in a primary care clinic with high TB and HIV prevalence in South Africa: a pragmatic randomised trial
    (Public Library of Science, 2014) Cox, Helen S; Mbhele, Slindile; Mohess, Neisha; Whitelaw, Andrew; Muller, Odelia; Zemanay, Widaad; Little, Francesca; Azevedo, Virginia; Simpson, John; Boehme, Catharina C; Nicol, Mark P
    Background: Xpert MTB/RIF is approved for use in tuberculosis (TB) and rifampicin-resistance diagnosis. However, data are limited on the impact of Xpert under routine conditions in settings with high TB burden. Methods and Findings: A pragmatic prospective cluster-randomised trial of Xpert for all individuals with presumptive (symptomatic) TB compared to the routine diagnostic algorithm of sputum microscopy and limited use of culture was conducted in a large TB/HIV primary care clinic. The primary outcome was the proportion of bacteriologically confirmed TB cases not initiating TB treatment by 3 mo after presentation. Secondary outcomes included time to TB treatment and mortality. Unblinded randomisation occurred on a weekly basis. Xpert and smear microscopy were performed on site. Analysis was both by intention to treat (ITT) and per protocol. Between 7 September 2010 and 28 October 2011, 1,985 participants were assigned to the Xpert (n = 982) and routine (n = 1,003) diagnostic algorithms (ITT analysis); 882 received Xpert and 1,063 routine (per protocol analysis). 13% (32/257) of individuals with bacteriologically confirmed TB (smear, culture, or Xpert) did not initiate treatment by 3 mo after presentation in the Xpert arm, compared to 25% (41/167) in the routine arm (ITT analysis, risk ratio 0.51, 95% CI 0.33–0.77, p = 0.0052). The yield of bacteriologically confirmed TB cases among patients with presumptive TB was 17% (167/1,003) with routine diagnosis and 26% (257/982) with Xpert diagnosis (ITT analysis, risk ratio 1.57, 95% CI 1.32–1.87, p<0.001). This difference in diagnosis rates resulted in a higher rate of treatment initiation in the Xpert arm: 23% (229/1,003) and 28% (277/982) in the routine and Xpert arms, respectively (ITT analysis, risk ratio 1.24, 95% CI 1.06–1.44, p = 0.013). Time to treatment initiation was improved overall (ITT analysis, hazard ratio 0.76, 95% CI 0.63–0.92, p = 0.005) and among HIV-infected participants (ITT analysis, hazard ratio 0.67, 95% CI 0.53–0.85, p = 0.001). There was no difference in 6-mo mortality with Xpert versus routine diagnosis. Study limitations included incorrect intervention allocation for a high proportion of participants and that the study was conducted in a single clinic. Conclusions: These data suggest that in this routine primary care setting, use of Xpert to diagnose TB increased the number of individuals with bacteriologically confirmed TB who were treated by 3 mo and reduced time to treatment initiation, particularly among HIV-infected participants.
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    An investigation into brand loyalty, and the case for house brands in the emergent township market
    (2000) Oakenfull, Catherine; Simpson, John
    Includes bibliographies.
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    An investigation into whether young teens change their clothing consumer behaviour and brand preferences after the transition from primary school (grade seven) to high school (grade eight) in the South Western Cape
    (2007) Fischer, Carolyn; Simpson, John
    This study focused on two segments that have emerged from an evolution within the children's market- the tween and young teen markets. However, few market researchers had investigated the transition between these two stages - leaving primary school and going to high school. Despite there being a rather small age gap between older tweens and young teens, the numerous challenges brought about due to the transition from primary school to high school could affect areas such as academic performance, friendships and so forth. It was the aim of this study to uncover any changes in relation to the consumer behaviour and brand preferences of young teens occurred due to this transitional period. The literature review looked at the international and South African older tween and young teen markets through market identification and characterization. The transition phase from primary school to high school looked at the similarities and differences of older tweens and young teens and the social and academic impact of school transitions on grade eights. Four areas were identified that were said to influence one's clothing consumer behaviour and brand preferences as a result of the school transition to high school. These were developmental changes; the influence of one's reference groups; role models and the media that one subscribes to, and the financial circumstances in which one lives. The researcher also investigated brand loyalty and the influence of peer pressure on the clothing consumer behaviour and brand preferences of young teens. Furthermore, the literature review covered branding and how fashion and brands influenced the consumer behaviour of young teens. Both quantitative and qualitative research methods were used in this study. The primary research tools used were the two surveys that were successfully administered to two hundred and seventy four grade sevens and eights in ten schools in the South Western Cape. Permission was obtained from the Western Cape Education Department and a time restriction was given for the surveys to be administered to the schools. The researcher also used qualitative research methods in the form of experience interviews with nine members of the academic and business community who were deemed knowledgeable on the topics of child development, branding, consumer behaviour and school transitions. Limited focus groups were conducted, although this was primarily used to construct the questionnaires. Furthermore, the researcher made use of secondary data sources such as reputable and peer reviewed journal articles, books and so forth. Out of the five school sets in this research study the De Kuilen school set showed statistically significant results between grade sevens and eights with regards to developmental, reference group, financial and brand preference changes. The Kuils River school set also showed statistically significant results with regards to developmental, role models, peer pressure and brand preference changes. However, the rest of the school sets showed minor or failed to show statistical differences between the two grades in question. On the whole no significant developmental, reference group, role model and peer pressure changes were noted between grade sevens and grade eights. On the other hand, two of the findings agreed with the initial hypotheses that were put forward. Financial changes did occur, as grade eights received more pocket money than grade sevens and parents were still involved in purchasing clothing for their young teens; and as expected, young teens failed to prove brand loyal. Consequently, although two null hypotheses (financial changes and brand loyalty) were accepted out of six proposed and two school sets out of the five showed statistical differences between the two grades on the matters investigated, the primary null hypothesis was rejected. The researcher concluded that young teens in the South Western Cape did not change their clothing consumer behaviour and brand preferences after entering high school. However, this conclusion was limited only to those schools and students who participated in the study. The researcher recommended that in general both grades could be targeted together as one clothing brand market. Especially when young teens were in the first part of grade eight, as both markets liked wearing brands such as Billabong and Roxy for very similar reasons. In addition, the lack of brand loyalty was not seen to be a hindrance, but an opportunity for marketers to attract young teens due to the fashionability and affordability of the clothing. Their purchasing power not only by themselves, but also more often than not with the help of their parents made them a lucrative market worthy of attention. On the other hand, while the researcher may have gained more knowledge from using more qualitative research, as some information from the questionnaires contradicted each other, it was also suggested that due the two age groups being so similar, it may have been more beneficial to compare two differing age groups such as grade sevens and nines.
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    A resource-based view of the firm : integrating the role of IT as a strategic resource - an empirical study of South African personal financial services (Assurance) firms, 1999-2003
    (2004) April, Kurt; Feeny, David; Simpson, John; Licker, Paul
    This research explores an "inside the black box" view on how IT enables sustainable competitive advantage. Most researchers have investigated IT competitive competencies that make up a firm's strategic framework to understand competitive advantage. However, Resource-Based Theory (RBT) probes into the inner workings of a firm, suggesting that a firm's IT assets and resources are the basis of a firm's "rare" core competencies to compete successfully. Using RBT and research in the economics, strategy, and IT literatures, an initial "Framework of Sustainability" was created, against which the case studies were conducted. This framework was used as foundation to develop semi-structured questionnaires in which 45, 90 minute (on average) interviews were conducted with managers in the four firms. Both internal and external documents about the firms and the industry were used as sources of corroborating evidence. In addition, a "bottoms up" view was obtained with evidence gathered from a short questionnaire and focus groups discussions held with 178 staff employees in the four firms.
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    Strategy and financial performance of South African industrial companies
    (1979) Andrews, Grenville Stafford; Simpson, John
    This thesis analyses the impact of strategy on the financial performance and risk of industrial firms quoted on the Johannesburg Stock Exchange over the period 1970 - 1976. This is the first study investigating the impact of strategy on economic performance in a developing economy and which utilizes a managerially orientated view of diversification to assess the association between strategy, performance and systematic risk. The strategic categorization scheme employed is based-on a-methodology which is common to exploratory studies carried out in more developed economies. Firms were placed into strategic categories based on the extent, manner and type of diversification that they exhibited. Four major and nine subcategories were identified. The results showed that South African industrial firms are not highly diversified and the composition of the firms suggest that they are at a stage of development that is comparable to that of the developed economies in 1950 when measured on the extent and manner of diversification. The growth and return performance of both major and sub-categories were analysed and a number of hypotheses were tested. The results showed that here are significant differences in performance between the categories and that utilizing the strategy classification system it was possible to distinguish between categories. In addition, the ranking of strat8gies, based on performance was -found to differ significantly from the United States research findings. An important aspect of the study was the evaluation of risk based on strategy.