Browsing by Author "Pineo, Catherine"

Now showing 1 - 1 of 1
  • Thumbnail Image
    Item
    Open Access
    Plant production and immunogenic characterisation of Human papillomavirus chimaeric vaccines
    (2011) Pineo, Catherine; Rybicki, Ed; Hitzeroth, Inga
    Cervical cancer is primarily caused by infection with Human papillomavirus (HPV) and is a global concern, particularly in developing countries which contain ~80% of the cervical cancer burden. Current HPV L1 major capsid protein virus-like particle (VLP)-based vaccines are effective in the type-specific prevention of infection and associated disease. However, the high cost of the vaccines has limited their widespread application, and cytological screening programmes are still required to detect malignant lesions associated with the non-vaccine types, particularly in HIV-infected populations.