Browsing by Author "Joubert, Ivan"

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    Open Access
    A retrospective descriptive analysis of prehospital advanced airway management in a South African private emergency medical service
    (2021) Araie, Farzana; Joubert, Ivan; Stassen, Willem
    Introduction: Emergency medical systems have evolved from mostly providing patient transport to healthcare facilities to the provision of emergency care interventions on scene or en route to a healthcare facility. Endotracheal intubation is one of these interventions but despite being performed in the prehospital setting for nearly two decades, the practice of prehospital ETI has not yet been examined on a national level. Methods: This is a retrospective chart review of prehospital ETI performed by non-physician prehospital providers of a ground-based emergency medical service that operates on a national level over a 12 month period. Results: Of the 806 cases recorded in the study period, 683 met the criteria for analysis. Male patients accounted for 67% of the cases. The majority of patients (56%) intubated were trauma patients while the remaining 44% were intubated for medical reasons. The first pass success rate was 74% and the overall success rate was 98%. Rapid sequence intubation was the method used to intubate 34% of patients. Approximately 29% received drug facilitated intubation and 27% of patients were intubated whilst being treated for cardiac arrest. Approximately 65% of patients had documented risk factors for difficult intubation. Clinical adverse events were recorded in 14% of cases. Discussion: The first pass success and overall success rates compare favourably with those reported in similar contexts. Adverse events were thought to be under-reported.
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    Open Access
    ICU-Associated Acinetobacter baumannii Colonisation/Infection in a High HIV-Prevalence Resource-Poor Setting
    (Public Library of Science, 2012) Ntusi, Ntobeko B A; Badri, Motasim; Khalfey, Hoosain; Whitelaw, Andrew; Oliver, Stephen; Piercy, Jenna; Raine, Richard; Joubert, Ivan; Dheda, Keertan
    BACKGROUND: There are hardly any data about the incidence, risk factors and outcomes of ICU-associated A.baumannii colonisation/infection in HIV-infected and uninfected persons from resource-poor settings like Africa. METHODS: We reviewed the case records of patients with A.baumannii colonisation/infection admitted into the adult respiratory and surgical ICUs in Cape Town, South Africa, from January 1 to December 31 2008. In contrast to colonisation, infection was defined as isolation of A.baumannii from any biological site in conjunction with a compatible clinical picture warranting treatment with antibiotics effective against A.baumannii . RESULTS: The incidence of A.baumannii colonisation/infection in 268 patients was 15 per 100 person-years, with an in-ICU mortality of 26.5 per 100 person-years. The average length of stay in ICU was 15 days (range 1-150). A.baumannii was most commonly isolated from the respiratory tract followed by the bloodstream. Independent predictors of mortality included older age (p = 0.02), low CD4 count if HIV-infected (p = 0.038), surgical intervention (p = 0.047), co-morbid Gram-negative sepsis (p = 0.01), high APACHE-II score (p = 0.001), multi-organ dysfunction syndrome (p = 0.012), and a positive blood culture for A.baumannii (p = 0.017). Of 21 A.baumannii colonised/infected HIV-positive persons those with clinical AIDS (CD4<200 cells/mm 3 ) had significantly higher in-ICU mortality and were more likely to have a positive blood culture. Conclusion In this resource-poor setting A.baumannii infection in critically ill patients is common and associated with high mortality. HIV co-infected patients with advanced immunosuppression are at higher risk of death.