Browsing by Author "Folefoc, Asongna Theresia Forkem"

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    Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5
    (2007) Folefoc, Asongna Theresia Forkem; Flanagan, Colleen; Katz, Arieh
    Four mutations of the CCR5 receptor have been identified in the South African population, but the effects of these mutations on CCR5 function and HIV infection are unknown. We have used in vitro methods to assess the ffect of the mutations, Asp2Val, Leu107Phe, Arg225Gln and Arg225stop, on CCR5 interactions with chemokine ligands and HIV.