Browsing by Author "Davis, Emily"
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- ItemOpen AccessMolecular characterization of ALDRXv4, an aldose reductase orthologue isolated from xerophyta viscosa, in response to abiotic stress(2005) Davis, Emily; Thomson, Jennifer Ann; Farrant, Jill M; Mundree, Sagadevan GIncludes bibliographical references (leaves 61-70).
- ItemOpen AccessThe role of the developmentally important transcription factor, TBX2, in the cell cycle and cancer(2009) Davis, Emily; Prince, SharonT-box factors play crucial roles in embryogenesis and mutations in T-box factor genes have been implicated in multiple human disorders. In addition, an increasing body of evidence implicates the T-box family in cell cycle regulation and in cancer...The aim of this study was therefore to address this question by establishing TBX2 over-expression and knockdown cell culture models. The results show that TBX2 does indeed contribute directly to the oncogenic process and further reveals a novel mechanism by which it contributes to tumourigenesis.